Research Progress in Milk-derived Exosomes

Milk exosomes are a newly discovered functional vesicles secreted by animal mammary epithelial cells, small vesicles with membrane structure in the diameter of about 30~200 nm, which contain many bioactive substances such as proteins, lipids, and nucleic acids on the surface and inside the membrane....

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Main Authors: Ying LI, Jingyao CHEN, Junying ZHAO, Xiaowen YU, Yihan YANG, Jufeng HU, Tiemin JIANG, Lijun CHEN
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2022-11-01
Series:Shipin gongye ke-ji
Subjects:
Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021090317
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author Ying LI
Jingyao CHEN
Junying ZHAO
Xiaowen YU
Yihan YANG
Jufeng HU
Tiemin JIANG
Lijun CHEN
author_facet Ying LI
Jingyao CHEN
Junying ZHAO
Xiaowen YU
Yihan YANG
Jufeng HU
Tiemin JIANG
Lijun CHEN
author_sort Ying LI
collection DOAJ
description Milk exosomes are a newly discovered functional vesicles secreted by animal mammary epithelial cells, small vesicles with membrane structure in the diameter of about 30~200 nm, which contain many bioactive substances such as proteins, lipids, and nucleic acids on the surface and inside the membrane. Recent studies have found exosomes with biological functions such as mediating cell communication, promoting cell proliferation, and participating in immune responses. Exosomes can be isolated from the emulsion by centrifugation, chemical, immunoaffinity and identified their morphology, size, specific substances. This article reviews the biological function, three omics studies, separation and identification methods, and aims to provide scientific reference for the research and development of milk source exosomes.
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publisher The editorial department of Science and Technology of Food Industry
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spelling doaj.art-a8ee45ea59cf4d13b2c0896fb076665b2022-12-22T02:52:36ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062022-11-01432240641310.13386/j.issn1002-0306.20210903172021090317-22Research Progress in Milk-derived ExosomesYing LI0Jingyao CHEN1Junying ZHAO2Xiaowen YU3Yihan YANG4Jufeng HU5Tiemin JIANG6Lijun CHEN7College of Food Science, Northeast Agricultural University, Harbin 150030, ChinaNational Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Food Co., Ltd., Beijing 100163, ChinaNational Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Food Co., Ltd., Beijing 100163, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaSouth Asia Branch of National Engineering Research Center of Dairy Health for Maternal and Child, Guilin University of Technology, Guilin 541006, ChinaCollege of Food Science, Northeast Agricultural University, Harbin 150030, ChinaMilk exosomes are a newly discovered functional vesicles secreted by animal mammary epithelial cells, small vesicles with membrane structure in the diameter of about 30~200 nm, which contain many bioactive substances such as proteins, lipids, and nucleic acids on the surface and inside the membrane. Recent studies have found exosomes with biological functions such as mediating cell communication, promoting cell proliferation, and participating in immune responses. Exosomes can be isolated from the emulsion by centrifugation, chemical, immunoaffinity and identified their morphology, size, specific substances. This article reviews the biological function, three omics studies, separation and identification methods, and aims to provide scientific reference for the research and development of milk source exosomes.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021090317milk derived exosomesbiological functionmulti-omics studyseparation and identification
spellingShingle Ying LI
Jingyao CHEN
Junying ZHAO
Xiaowen YU
Yihan YANG
Jufeng HU
Tiemin JIANG
Lijun CHEN
Research Progress in Milk-derived Exosomes
Shipin gongye ke-ji
milk derived exosomes
biological function
multi-omics study
separation and identification
title Research Progress in Milk-derived Exosomes
title_full Research Progress in Milk-derived Exosomes
title_fullStr Research Progress in Milk-derived Exosomes
title_full_unstemmed Research Progress in Milk-derived Exosomes
title_short Research Progress in Milk-derived Exosomes
title_sort research progress in milk derived exosomes
topic milk derived exosomes
biological function
multi-omics study
separation and identification
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021090317
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