Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s Perspective
Introduction: Autopsy aids to the knowledge of pathology by unveiling the rare lesions which are a source of learning from a pathologist’s perspective Some of them are only diagnosed at autopsy as they do not cause any functional derangement. This study emphasizes the various incidental lesions...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2016-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8850/21106_CE[Ra]_F(Sh)_PF1(GU_SRI)_PFA(AK)_PF2(OPR_P).pdf |
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| author | SAPNA PATEL B.R. RAJALAKSHMI G.V.MANJUNATH |
| author_facet | SAPNA PATEL B.R. RAJALAKSHMI G.V.MANJUNATH |
| author_sort | SAPNA PATEL |
| collection | DOAJ |
| description | Introduction: Autopsy aids to the knowledge of pathology by
unveiling the rare lesions which are a source of learning from
a pathologist’s perspective Some of them are only diagnosed
at autopsy as they do not cause any functional derangement.
This study emphasizes the various incidental lesions which
otherwise would have been unnoticed during a person’s life.
Aim: The aim of this study was to determine the spectrum of
histopathological findings including neoplastic lesions related
or unrelated to the cause of death. It was also aimed to highlight
various incidental and interesting lesions in autopsies.
Materials and Methods: A retrospective study of medicolegal
autopsies for six years was undertaken in a tertiary care
centre to determine the spectrum of histopathological findings
including neoplastic lesions related or unrelated to the cause of
death and to highlight various incidental and interesting lesions
in autopsies.
Statistical Analysis: Individual lesions were described in
numbers and incidence in percentage.
Results: The study consisted of a series of 269 autopsy cases
and histopathological findings were studied only in 202 cases.
The commonest cause of death was pulmonary oedema. The
most common incidental histopathological finding noted was
atherosclerosis in 55 (27.2%) cases followed by fatty liver in
40 (19.8%) cases. Neoplastic lesions accounted for 2.47% of
cases.
Conclusion: This study has contributed a handful of findings
to the pool of rare lesions in pathology. Some of these lesions
encountered which served as feast to a pathologist are
tumour to tumour metastasis, a case with coexistent triple
lesions, Dubin Johnson syndrome, von Meyenburg complex,
Multilocular Cystic Renal Cell Carcinoma (MCRCC), Autosomal
Dominant Polycystic Kidney Disease (ADPKD), liver carcinod
and an undiagnosed vaso-occlusive sickle cell crisis. Autopsy
studies help in the detection of unexpected findings significant
enough to have changed patient management had they been
recognized before death. |
| first_indexed | 2024-12-11T05:52:26Z |
| format | Article |
| id | doaj.art-a8f0e0a5741c4946832d74b5f1e3d64d |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T05:52:26Z |
| publishDate | 2016-11-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-a8f0e0a5741c4946832d74b5f1e3d64d2022-12-22T01:18:47ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-11-011011EC08EC1210.7860/JCDR/2016/21106.8850Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s PerspectiveSAPNA PATEL0B.R. RAJALAKSHMI1G.V.MANJUNATH2Assistant Professor, Department of Pathology, JSS Medical College, JSS University, Mysuru, India.Assistant Professor, Department of Pathology, JSS Medical College, JSS University, Mysuru, India.Professor and HOD, Department of Pathology, JSS Medical College, JSS University, Mysuru, India.Introduction: Autopsy aids to the knowledge of pathology by unveiling the rare lesions which are a source of learning from a pathologist’s perspective Some of them are only diagnosed at autopsy as they do not cause any functional derangement. This study emphasizes the various incidental lesions which otherwise would have been unnoticed during a person’s life. Aim: The aim of this study was to determine the spectrum of histopathological findings including neoplastic lesions related or unrelated to the cause of death. It was also aimed to highlight various incidental and interesting lesions in autopsies. Materials and Methods: A retrospective study of medicolegal autopsies for six years was undertaken in a tertiary care centre to determine the spectrum of histopathological findings including neoplastic lesions related or unrelated to the cause of death and to highlight various incidental and interesting lesions in autopsies. Statistical Analysis: Individual lesions were described in numbers and incidence in percentage. Results: The study consisted of a series of 269 autopsy cases and histopathological findings were studied only in 202 cases. The commonest cause of death was pulmonary oedema. The most common incidental histopathological finding noted was atherosclerosis in 55 (27.2%) cases followed by fatty liver in 40 (19.8%) cases. Neoplastic lesions accounted for 2.47% of cases. Conclusion: This study has contributed a handful of findings to the pool of rare lesions in pathology. Some of these lesions encountered which served as feast to a pathologist are tumour to tumour metastasis, a case with coexistent triple lesions, Dubin Johnson syndrome, von Meyenburg complex, Multilocular Cystic Renal Cell Carcinoma (MCRCC), Autosomal Dominant Polycystic Kidney Disease (ADPKD), liver carcinod and an undiagnosed vaso-occlusive sickle cell crisis. Autopsy studies help in the detection of unexpected findings significant enough to have changed patient management had they been recognized before death.https://jcdr.net/articles/PDF/8850/21106_CE[Ra]_F(Sh)_PF1(GU_SRI)_PFA(AK)_PF2(OPR_P).pdfdubin johnson syndromemedicolegal autopsiesmultilocular cystic rccvaso-occlusive crisis |
| spellingShingle | SAPNA PATEL B.R. RAJALAKSHMI G.V.MANJUNATH Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s Perspective Journal of Clinical and Diagnostic Research dubin johnson syndrome medicolegal autopsies multilocular cystic rcc vaso-occlusive crisis |
| title | Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s Perspective |
| title_full | Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s Perspective |
| title_fullStr | Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s Perspective |
| title_full_unstemmed | Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s Perspective |
| title_short | Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist’s Perspective |
| title_sort | histopathologic findings in autopsies with emphasis on interesting and incidental findings a pathologist s perspective |
| topic | dubin johnson syndrome medicolegal autopsies multilocular cystic rcc vaso-occlusive crisis |
| url | https://jcdr.net/articles/PDF/8850/21106_CE[Ra]_F(Sh)_PF1(GU_SRI)_PFA(AK)_PF2(OPR_P).pdf |
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