Regulation of the Voltage Gated K+ Channel Kv1.3 by Recombinant Human Klotho Protein

Regulation of the Voltage Gated K+ Channel Kv1.3 by Recombinant Human Klotho Protein

Background/Aims: Klotho, a protein mainly produced in the kidney and released into circulating blood, contributes to the negative regulation of 1,25(OH)2D3 formation and is thus a powerful regulator of mineral metabolism. As β-glucuronidase, alpha Klotho protein further regulates the stability of se...

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Bibliographic Details
Main Authors: Ahmad Almilaji, Sabina Honisch, Guilai Liu, Bernat Elvira, Sumant Singh Ajay, Zohreh Hosseinzadeh, Musaab Ahmed, Carlos Munoz, Mentor Sopjani, Florian Lang
Format: Article
Language:English
Published: Karger Publishers 2014-12-01
Series:Kidney & Blood Pressure Research
Subjects:
Alpha Klotho protein
Recombinant human Klotho protein
Kv1.3 channel
Xenopus oocytes
Jcam cells
Online Access:http://www.karger.com/Article/FullText/368472

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