Thrombosis in patients with myeloproliferative neoplasms. Case report
Thrombotic complications are the most significant factors determining the prognosis in myeloproliferative neoplasms. Markers for assessing the risk of thrombosis are the number of leukocytes, platelets, hemoglobin level, hematocrit, age, molecular status, history of thrombosis, obesity, arterial hyp...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2021-07-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/76322/56910 |
| _version_ | 1819066381194231808 |
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| author | Anait L. Melikyan Irina N. Subortseva Elena A. Gilyazitdinova Tamara I. Koloshejnova Kristina S. Shashkina Elena K. Egorova Alla M. Kovrigina Andrei B. Sudarikov Lana A. Gorgidze |
| author_facet | Anait L. Melikyan Irina N. Subortseva Elena A. Gilyazitdinova Tamara I. Koloshejnova Kristina S. Shashkina Elena K. Egorova Alla M. Kovrigina Andrei B. Sudarikov Lana A. Gorgidze |
| author_sort | Anait L. Melikyan |
| collection | DOAJ |
| description | Thrombotic complications are the most significant factors determining the prognosis in myeloproliferative neoplasms. Markers for assessing the risk of thrombosis are the number of leukocytes, platelets, hemoglobin level, hematocrit, age, molecular status, history of thrombosis, obesity, arterial hypertension, hyperlipidemia, hereditary or acquired thrombophilia. The pathogenesis of thrombosis in patients with myeloproliferative neoplasms is complex and multifactorial. In most cases, the etiological factor remains unknown. Currently, antiplatelet and anticoagulant therapy is carried out on an individual basis. The algorithm for primary and secondary (after thrombosis) prevention requires development and testing. We present a clinical case of repeated arterial and venous thrombotic complications in a patient with primary myelofibrosis. |
| first_indexed | 2024-12-21T16:01:27Z |
| format | Article |
| id | doaj.art-a8f529a9d51348999edede08c2a89361 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-21T16:01:27Z |
| publishDate | 2021-07-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-a8f529a9d51348999edede08c2a893612022-12-21T18:57:59Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422021-07-0193780080410.26442/00403660.2021.07.20092569931Thrombosis in patients with myeloproliferative neoplasms. Case reportAnait L. Melikyan0https://orcid.org/0000-0002-2119-3775Irina N. Subortseva1https://orcid.org/0000-0001-9045-8653Elena A. Gilyazitdinova2https://orcid.org/0000-0002-3883-185XTamara I. Koloshejnova3https://orcid.org/0000-0003-4580-040XKristina S. Shashkina4https://orcid.org/0000-0003-1974-4870Elena K. Egorova5https://orcid.org/0000-0001-6038-9474Alla M. Kovrigina6https://orcid.org/0000-0002-1082-8659Andrei B. Sudarikov7https://orcid.org/0000-0001-9463-9187Lana A. Gorgidze8https://orcid.org/0000-0001-5235-2356National Research Center for HematologyNational Research Center for HematologyNational Research Center for HematologyNational Research Center for HematologyNational Research Center for HematologyNational Research Center for HematologyNational Research Center for HematologyNational Research Center for HematologyNational Research Center for HematologyThrombotic complications are the most significant factors determining the prognosis in myeloproliferative neoplasms. Markers for assessing the risk of thrombosis are the number of leukocytes, platelets, hemoglobin level, hematocrit, age, molecular status, history of thrombosis, obesity, arterial hypertension, hyperlipidemia, hereditary or acquired thrombophilia. The pathogenesis of thrombosis in patients with myeloproliferative neoplasms is complex and multifactorial. In most cases, the etiological factor remains unknown. Currently, antiplatelet and anticoagulant therapy is carried out on an individual basis. The algorithm for primary and secondary (after thrombosis) prevention requires development and testing. We present a clinical case of repeated arterial and venous thrombotic complications in a patient with primary myelofibrosis.https://ter-arkhiv.ru/0040-3660/article/viewFile/76322/56910myeloproliferative neoplasmsthrombosisprimary myelofibrosis |
| spellingShingle | Anait L. Melikyan Irina N. Subortseva Elena A. Gilyazitdinova Tamara I. Koloshejnova Kristina S. Shashkina Elena K. Egorova Alla M. Kovrigina Andrei B. Sudarikov Lana A. Gorgidze Thrombosis in patients with myeloproliferative neoplasms. Case report Терапевтический архив myeloproliferative neoplasms thrombosis primary myelofibrosis |
| title | Thrombosis in patients with myeloproliferative neoplasms. Case report |
| title_full | Thrombosis in patients with myeloproliferative neoplasms. Case report |
| title_fullStr | Thrombosis in patients with myeloproliferative neoplasms. Case report |
| title_full_unstemmed | Thrombosis in patients with myeloproliferative neoplasms. Case report |
| title_short | Thrombosis in patients with myeloproliferative neoplasms. Case report |
| title_sort | thrombosis in patients with myeloproliferative neoplasms case report |
| topic | myeloproliferative neoplasms thrombosis primary myelofibrosis |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/76322/56910 |
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