Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil.
<h4>Introduction</h4>The aim of the study was to identify factors associated with the causes of in-hospital morbidity and mortality in an elderly Brazilian population due to osteoporotic hip fractures.<h4>Method</h4>Retrospective cohort study involving a population over 60 ye...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0272006 |
| _version_ | 1811188740694999040 |
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| author | Viviane Cristina Uliana Peterle Maria Rita Carvalho Garbi Novaes Paulo Emiliano Bezerra Junior João Carlos Geber Júnior Rodrigo Tinôco Magalhães Cavalcante Jurandi Barrozo da Silva Junior Ray Costa Portela Ana Patricia de Paula |
| author_facet | Viviane Cristina Uliana Peterle Maria Rita Carvalho Garbi Novaes Paulo Emiliano Bezerra Junior João Carlos Geber Júnior Rodrigo Tinôco Magalhães Cavalcante Jurandi Barrozo da Silva Junior Ray Costa Portela Ana Patricia de Paula |
| author_sort | Viviane Cristina Uliana Peterle |
| collection | DOAJ |
| description | <h4>Introduction</h4>The aim of the study was to identify factors associated with the causes of in-hospital morbidity and mortality in an elderly Brazilian population due to osteoporotic hip fractures.<h4>Method</h4>Retrospective cohort study involving a population over 60 years of age admitted to hospital due to osteoporotic hip fractures and followed up from hospitalization to outcome (discharge or mortality) from 2010 to 2018, in a public hospital in Brasília, the capital of Brazil. Multivariate analysis was performed using the Poisson regression model with a robust variance, observing the hierarchical model proposed and the receiver operating characteristic (ROC) curve to obtain the cutoff point for mortality incidence in relation the total length of hospital stay. Significance level was set as p < 0.05. The analyses were conducted using the SAS 9.4 software.<h4>Result</h4>The mean hospital mortality rate among the 402 patients involved was 18.4%, and the associations made with the outcome mortality were per relevance: respiratory infection, age over 90 years, high preoperative cardiovascular risk, chronic obstructive pulmonary disease (COPD) as comorbidity, serum hemoglobin level ≤ 10 and other infections. Mortality also showed association with longer total length of hospital stay, as well as with prolonged postoperative period.<h4>Conclusion</h4>Hip fractures in the elderly due to osteoporosis indicate a relationship between the sicker profile of the aging elderly population and the prevalence of chronic diseases strongly associated with in-hospital infections, contributing to increased mortality. There were fewer early interventions, and mortality was also associated with prolonged postoperative period. The aim of this study was not to compare independent variables with each other, but suggests the relationship between the presence of comorbidities, which predisposes to the development of infections, directly linked to mortality. |
| first_indexed | 2024-04-11T14:24:46Z |
| format | Article |
| id | doaj.art-a8f635c1d28b4d41a527727087731a67 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-11T14:24:46Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a8f635c1d28b4d41a527727087731a672022-12-22T04:18:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01178e027200610.1371/journal.pone.0272006Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil.Viviane Cristina Uliana PeterleMaria Rita Carvalho Garbi NovaesPaulo Emiliano Bezerra JuniorJoão Carlos Geber JúniorRodrigo Tinôco Magalhães CavalcanteJurandi Barrozo da Silva JuniorRay Costa PortelaAna Patricia de Paula<h4>Introduction</h4>The aim of the study was to identify factors associated with the causes of in-hospital morbidity and mortality in an elderly Brazilian population due to osteoporotic hip fractures.<h4>Method</h4>Retrospective cohort study involving a population over 60 years of age admitted to hospital due to osteoporotic hip fractures and followed up from hospitalization to outcome (discharge or mortality) from 2010 to 2018, in a public hospital in Brasília, the capital of Brazil. Multivariate analysis was performed using the Poisson regression model with a robust variance, observing the hierarchical model proposed and the receiver operating characteristic (ROC) curve to obtain the cutoff point for mortality incidence in relation the total length of hospital stay. Significance level was set as p < 0.05. The analyses were conducted using the SAS 9.4 software.<h4>Result</h4>The mean hospital mortality rate among the 402 patients involved was 18.4%, and the associations made with the outcome mortality were per relevance: respiratory infection, age over 90 years, high preoperative cardiovascular risk, chronic obstructive pulmonary disease (COPD) as comorbidity, serum hemoglobin level ≤ 10 and other infections. Mortality also showed association with longer total length of hospital stay, as well as with prolonged postoperative period.<h4>Conclusion</h4>Hip fractures in the elderly due to osteoporosis indicate a relationship between the sicker profile of the aging elderly population and the prevalence of chronic diseases strongly associated with in-hospital infections, contributing to increased mortality. There were fewer early interventions, and mortality was also associated with prolonged postoperative period. The aim of this study was not to compare independent variables with each other, but suggests the relationship between the presence of comorbidities, which predisposes to the development of infections, directly linked to mortality.https://doi.org/10.1371/journal.pone.0272006 |
| spellingShingle | Viviane Cristina Uliana Peterle Maria Rita Carvalho Garbi Novaes Paulo Emiliano Bezerra Junior João Carlos Geber Júnior Rodrigo Tinôco Magalhães Cavalcante Jurandi Barrozo da Silva Junior Ray Costa Portela Ana Patricia de Paula Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil. PLoS ONE |
| title | Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil. |
| title_full | Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil. |
| title_fullStr | Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil. |
| title_full_unstemmed | Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil. |
| title_short | Osteoporotic hip fracture-Comorbidities and factors associated with in-hospital mortality in the elderly: A nine-year cohort study in Brazil. |
| title_sort | osteoporotic hip fracture comorbidities and factors associated with in hospital mortality in the elderly a nine year cohort study in brazil |
| url | https://doi.org/10.1371/journal.pone.0272006 |
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