A Fluorine-19 Magnetic Resonance Probe, Shiga-Y5, Downregulates Thioredoxin-Interacting Protein Expression in the Brain of a Mouse Model of Alzheimer’s Disease

A Fluorine-19 Magnetic Resonance Probe, Shiga-Y5, Downregulates Thioredoxin-Interacting Protein Expression in the Brain of a Mouse Model of Alzheimer’s Disease

Thioredoxin-interacting protein (<i>TXNIP</i>) is involved in multiple disease-associated functions related to oxidative stress, especially by inhibiting the anti-oxidant- and thiol-reducing activity of thioredoxin (<i>TXN</i>). Shiga-Y5 (SY5), a fluorine-19 magnetic resonanc...

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Bibliographic Details
Main Authors: Aslina Pahrudin Arrozi, Zulzikry Hafiz Abu Bakar, Hiroyasu Taguchi, Daijiro Yanagisawa, Ikuo Tooyama
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
curcumin
oxidative stress
thioredoxin
<i>TXNIP</i>
Alzheimer’s disease
Online Access:https://www.mdpi.com/1420-3049/26/17/5342

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