Role of D1/D2 dopamin receptors antagonist perphenazine in morphine analgesia and tolerance in rats

Role of D1/D2 dopamin receptors antagonist perphenazine in morphine analgesia and tolerance in rats

While opioid receptors have been implicated in the development of tolerance, the subsequent mechanisms involved in these phenomena have not been completely understood. The purpose of this study was to investigate effects of D1/D2 dopamine receptors antagonist perphenazine on morphine analgesia and t...

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Bibliographic Details
Main Authors: Ercan Ozdemir, Ihsan Bagcivan, Sinan Gursoy
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2013-05-01
Series:Biomolecules & Biomedicine
Subjects:
dopamine receptors
perphenazine
analgesia
morphine tolerance
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/2394

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