Extracellular matrix composition affects outgrowth of dendrites and dendritic spines on cortical neurons

Extracellular matrix composition affects outgrowth of dendrites and dendritic spines on cortical neurons

The composition of the extracellular matrix (ECM) in nervous tissue plays an important role in controlling neuronal outgrowth and synapse development. Changes in both protein and glycosaminoglycan components of the ECM occur with tissue injury and may affect neuron growth. To investigate neuron resp...

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Bibliographic Details
Main Authors: Archana Sharma, Katherine E. Hill, Jean E. Schwarzbauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
decellularized ECM
fibronectin
tenascin-C
cortical neurons
dendrites
spines
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1177663/full

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