Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis

Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis

Summary: Spermatogonial stem cells (SSCs) both self-renew and give rise to progenitors that initiate spermatogenic differentiation in the mammalian testis. Questions remain regarding the extent to which the SSC and progenitor states are functionally distinct. Here we provide the first multiparametri...

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Bibliographic Details
Main Authors: Keren Cheng, I-Chung Chen, Ching-Hsun Eric Cheng, Kazadi Mutoji, Benjamin J. Hale, Brian P. Hermann, Christopher B. Geyer, Jon M. Oatley, John R. McCarrey
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Developmental Genetics
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307884

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