Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Ovalbumin-Specific Cell Mediated Immunity in Mice Model

Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Ovalbumin-Specific Cell Mediated Immunity in Mice Model

Induction of antigen-specific cell-mediated immunity (CMI), as well as humoral immunity, is critical for successful vaccination against various type of pathogens. Toll-like receptor (TLR) agonists have been developed as adjuvants to promote vaccine efficacy and induce appropriate immune responses. M...

Full description

Bibliographic Details
Main Authors:	So Yeon Ahn, Chau Thuy Tien Le, Eun-Ju Ko
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	Biology
Subjects:	cell-mediated immunity memory T cell dendritic cell monophosphoryl lipid A Poly I:C
Online Access:	https://www.mdpi.com/2079-7737/10/9/908

Similar Items

Functional NK Cell Activation by Ovalbumin Immunization with a Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Dendritic Cell Maturation
by: Chau Thuy Tien Le, et al.
Published: (2021-09-01)

Mechanism of activation of porcine dendritic cells by an α-D-glucan nanoparticle adjuvant and a nanoparticle/poly(I:C) combination adjuvant
by: Juan F. Hernandez-Franco, et al.
Published: (2022-09-01)

Effect of Monophosphoryl Lipid A on Lipopolysaccharide-Induced Nitric Oxide Production from Raw 264.7 Macrophages
by: Cemalettin AYBAY, et al.
Published: (1997-06-01)

LN Monocytes Limit DC-Poly I:C Induced Cytotoxic T Cell Response via IL-10 and Induction of Suppressor CD4 T Cells
by: Anita Tewari, et al.
Published: (2021-10-01)

Gemcitabine and doxorubicin in immunostimulatory monophosphoryl lipid A liposomes for treating breast cancer
by: Debra Wu, et al.
Published: (2021-01-01)

Poly I:C Pre-Treatment Induced the Anti-Viral Interferon Response in Airway Epithelial Cells
by: Hannah Mitländer, et al.
Published: (2023-11-01)

Adjuvant effects of combination monophosphoryl lipid A and poly I:C on antigen-specific immune responses and protective efficacy of influenza vaccines
by: Chau Thuy Tien Le, et al.
Published: (2023-07-01)

A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy
by: Jorrit De Waele, et al.
Published: (2021-06-01)

Immune System Modulation by the Adjuvants Poly (I:C) and Montanide ISA 720
by: Rodolfo F. Marques, et al.
Published: (2022-06-01)

Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials
by: Fučíková Jitka, et al.
Published: (2011-12-01)

A real-time 31P-NMR-based approach for the assessment of glycerol kinase catalyzed monophosphorylations
by: Wendy Escobedo-Hinojosa, et al.
Published: (2021-01-01)

Toll-like receptor 4 stimulation with monophosphoryl lipid A ameliorates motor deficits and nigral neurodegeneration triggered by extraneuronal α-synucleinopathy
by: Serena Venezia, et al.
Published: (2017-07-01)

ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells
by: Gemma Laura, et al.
Published: (2021-05-01)

Poly(I:C) and R848 ligands show better adjuvanticity to induce B and T cell responses against the antigen(s)
by: Nikunj Tandel, et al.
Published: (2024-03-01)

Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype
by: Xingdong Guo, et al.
Published: (2022-12-01)

A Nanoparticle-Poly(I:C) Combination Adjuvant Enhances the Breadth of the Immune Response to Inactivated Influenza Virus Vaccine in Pigs
by: Sankar Renu, et al.
Published: (2020-05-01)

Targeting the immune system to fight cancer using chemical receptor homing vectors carrying Poly Inosine/Cytosine (PolyIC)
by: Alexander eLevitzki
Published: (2012-02-01)

Non-Viable Lactobacillus Casei Beneficially Modulates Poly I:C Immune Response in Co-Cultures of Human Cells
by: Elisa Vintiñi, et al.
Published: (2017-12-01)

<i>E. coli</i>-Produced Monophosphoryl Lipid a Significantly Enhances Protective Immunity of Pandemic H1N1 Vaccine
by: Quyen Thi Nguyen, et al.
Published: (2020-06-01)

Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the Chikungunya virus in BEAS-2B cells
by: Li Yong-Gang, et al.
Published: (2012-06-01)

Combined Adjuvant of Poly I:C Improves Antitumor Effects of CAR-T Cells
by: Shengmeng Di, et al.
Published: (2019-04-01)

The Use of an Adjuvant System Improves Innate and Adaptive Immune Response When Associated with a <i>Leishmania</i> (<i>Viannia</i>) <i>braziliensis</i> Antigen in a Vaccine Candidate against <i>L.</i> (<i>Leishmania</i>) <i>infantum</i> Infection
by: Fernando Augusto Siqueira Mathias, et al.
Published: (2023-02-01)

Amplifying Immune Responses: Microparticulate Vaccine Approach Against Breast Cancer
by: Ubowski MM, et al.
Published: (2024-03-01)

QS21-Initiated Fusion of Liposomal Small Unilamellar Vesicles to Form ALFQ Results in Concentration of Most of the Monophosphoryl Lipid A, QS21, and Cholesterol in Giant Unilamellar Vesicles
by: Erwin G. Abucayon, et al.
Published: (2023-08-01)

Pre-treatment with the viral Toll-like receptor 3 agonist poly(I:C) modulates innate immunity and protects neutropenic mice infected intracerebrally with Escherichia coli
by: Sandra Ribes, et al.
Published: (2020-01-01)

A formulated poly (I:C)/CCL21 as an effective mucosal adjuvant for gamma-irradiated influenza vaccine
by: Ailar Sabbaghi, et al.
Published: (2021-10-01)

Is adjuvant chemotherapy beneficial for patients with FIGO stage IC adult granulosa cell tumor of the ovary?
by: Dan Wang, et al.
Published: (2018-03-01)

A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation
by: Donghui Yang, et al.
Published: (2024-02-01)

Inhibition of PI3Kδ Enhances Poly I:C-Induced Antiviral Responses and Inhibits Replication of Human Metapneumovirus in Murine Lungs and Human Bronchial Epithelial Cells
by: Akitaka Fujita, et al.
Published: (2020-03-01)

Erythromycin treatment hinders the induction of oral tolerance to fed ovalbumin
by: Sydney E. Lambert, et al.
Published: (2012-07-01)

Transcriptomic basis of neutrophil ratio variation induced by poly I:C stimulation in porcine peripheral blood
by: Haiyan WANG, Qiaoxia ZHANG, Lilin YIN, Xiangdong LIU, Shuhong ZHAO, Mengjin ZHU, Changchun LI
Published: (2017-09-01)

The effects of urolithin A on poly I:C-induced microglial activation
by: Yakum Benard Mingo, et al.
Published: (2024-03-01)

Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)
by: Signe Tandrup Schmidt, et al.
Published: (2018-04-01)

poly(I:C) synergizes with proteasome inhibitors to induce apoptosis in cervical cancer cells
by: Xueqiong Meng, et al.
Published: (2022-04-01)

CD68+ Macrophage Infiltration Associates With Poor Outcome of HPV Negative Oral Squamous Carcinoma Patients Receiving Radiation: Poly(I:C) Enhances Radiosensitivity of CAL-27 Cells but Promotes Macrophage Recruitment Through HMGB1
by: Dan Ai, et al.
Published: (2021-09-01)

Priming With Toll-Like Receptor 3 Agonist Poly(I:C) Enhances Content of Innate Immune Defense Proteins but Not MicroRNAs in Human Mesenchymal Stem Cell-Derived Extracellular Vesicles
by: Lisa M. Pierce, et al.
Published: (2021-05-01)

Sex differences and similarities in the neuroimmune response to central administration of poly I:C
by: Caitlin K. Posillico, et al.
Published: (2021-09-01)

Poly(I:C), a double stranded RNA analog, activates the anti-viral DNA sensors in buffalo fibroblasts
by: Jatinder Singh Chera, et al.
Published: (2023-03-01)

Clozapine Prevents Poly (I:C) Induced Inflammation by Modulating NLRP3 Pathway in Microglial Cells
by: Vijayasree V. Giridharan, et al.
Published: (2020-02-01)

Dexamethasone and monophosphoryl lipid A-modulated dendritic cells promote antigen-specific tolerogenic properties on naïve and memory CD4+ T cells
by: Jaxaira Maggi, et al.
Published: (2016-09-01)