Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental disorder characterized by attention deficit, hyperactivity, and impulsivity. ADHD presents impairments in academic, social, emotional and cognitive domains. Genetic and environmental factors play a role in the etiology o...

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Main Author: Canan Kuygun Karcı
Format: Article
Language:English
Published: Psikiyatride Güncel Yaklaşımlar 2021-09-01
Series:Psikiyatride Güncel Yaklaşımlar
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/1349618
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author Canan Kuygun Karcı
author_facet Canan Kuygun Karcı
author_sort Canan Kuygun Karcı
collection DOAJ
description Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental disorder characterized by attention deficit, hyperactivity, and impulsivity. ADHD presents impairments in academic, social, emotional and cognitive domains. Genetic and environmental factors play a role in the etiology of ADHD. Numerous studies showed that parameters associated with inflammation were higher in patients with ADHD. Due to the co-occurrence of ADHD and allergic and immunologic disorders, it is thought that the immune system has an effect on ADHD etiology. Previous studies showed that there is a strong association between prenatal inflammation exposure and neurodevelopmental disorders. Maternal diabetes mellitus, body mass index, preeclampsia, infections and chronic or autoimmune disorders of the mother are accepted as prenatal risk factors of ADHD. All these risk factors are associated with the immune profile of the mother. Because of this, the association between ADHD and intrauterine inflammation exposure is attractive. In this paper, the association of ADHD and perinatal inflammation due to maternal immune activation is reviewed.
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spelling doaj.art-a90ca77df27f41239ccbf9410224b6542024-02-03T05:13:11ZengPsikiyatride Güncel YaklaşımlarPsikiyatride Güncel Yaklaşımlar1309-06581309-06742021-09-0113347848910.18863/pgy.811846496Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity DisorderCanan Kuygun KarcıAttention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental disorder characterized by attention deficit, hyperactivity, and impulsivity. ADHD presents impairments in academic, social, emotional and cognitive domains. Genetic and environmental factors play a role in the etiology of ADHD. Numerous studies showed that parameters associated with inflammation were higher in patients with ADHD. Due to the co-occurrence of ADHD and allergic and immunologic disorders, it is thought that the immune system has an effect on ADHD etiology. Previous studies showed that there is a strong association between prenatal inflammation exposure and neurodevelopmental disorders. Maternal diabetes mellitus, body mass index, preeclampsia, infections and chronic or autoimmune disorders of the mother are accepted as prenatal risk factors of ADHD. All these risk factors are associated with the immune profile of the mother. Because of this, the association between ADHD and intrauterine inflammation exposure is attractive. In this paper, the association of ADHD and perinatal inflammation due to maternal immune activation is reviewed.https://dergipark.org.tr/tr/download/article-file/1349618inflammationattention deficit hyperactivity disorderimmune activation
spellingShingle Canan Kuygun Karcı
Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity Disorder
Psikiyatride Güncel Yaklaşımlar
inflammation
attention deficit hyperactivity disorder
immune activation
title Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity Disorder
title_full Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity Disorder
title_fullStr Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity Disorder
title_full_unstemmed Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity Disorder
title_short Relationship between Prenatal Inflammation and Attention Deficit Hyperactivity Disorder
title_sort relationship between prenatal inflammation and attention deficit hyperactivity disorder
topic inflammation
attention deficit hyperactivity disorder
immune activation
url https://dergipark.org.tr/tr/download/article-file/1349618
work_keys_str_mv AT canankuygunkarcı relationshipbetweenprenatalinflammationandattentiondeficithyperactivitydisorder