Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern India
Background: Fetal origin of cardiovascular diseases (CVD) hypothesis has been explored mostly in retrospective studies. Objectives: A prospective study was conducted to find the association of birth weight with CVD risk factors. Methods: A cohort of 243 babies born in 1992–1993 in ten villages of Ra...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Public Health |
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| Online Access: | http://www.ijph.in/article.asp?issn=0019-557X;year=2022;volume=66;issue=1;spage=9;epage=14;aulast=Valecha |
| _version_ | 1817992810008150016 |
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| author | Divya Valecha P. V. M. Lakshmi Naresh Sachdeva Rajesh Kumar |
| author_facet | Divya Valecha P. V. M. Lakshmi Naresh Sachdeva Rajesh Kumar |
| author_sort | Divya Valecha |
| collection | DOAJ |
| description | Background: Fetal origin of cardiovascular diseases (CVD) hypothesis has been explored mostly in retrospective studies. Objectives: A prospective study was conducted to find the association of birth weight with CVD risk factors. Methods: A cohort of 243 babies born in 1992–1993 in ten villages of Raipur Rani Block in India, were followed-up in 2016–2017. WHO STEPS methods were used to assess the risk factors of CVDs. A total of 213 (87.8%) participants were examined; blood samples were collected from 207. Multivariable regression analysis was done to adjust for the confounding variables. Results: Study participants were 22–24 year old, 27.7% were exposed to tobacco and 24.8% consumed alcohol, 3.3% were taking >5 servings of fruits and vegetables per day, 35.7% were physically inactive, 28.6% were overweight (body mass index [BMI] ≥23 kg/m2), 12.2% had hypertension, 16% had high cholesterol (≥200 mg/dl), 16.4% had insulin resistance (IR) (Homeostatic Model Assessment-IR >3), and 20.7% were born with low birth weight (<2.5 kg). Multivariable regression analysis revealed inverse relationship between birth weight and systolic blood pressure (regression coefficient ‒3.72 mmHg, 95% confidence interval ‒7.249; ‒0.183, P < 0.05). Conclusion: Birth weight has inverse relationship with blood pressure. Effect of birth weight on CVDs should also be studied in future follow-ups. |
| first_indexed | 2024-04-14T01:31:15Z |
| format | Article |
| id | doaj.art-a90edff82cbd4132a87945b1dbc0672f |
| institution | Directory Open Access Journal |
| issn | 0019-557X |
| language | English |
| last_indexed | 2024-04-14T01:31:15Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Public Health |
| spelling | doaj.art-a90edff82cbd4132a87945b1dbc0672f2022-12-22T02:20:12ZengWolters Kluwer Medknow PublicationsIndian Journal of Public Health0019-557X2022-01-0166191410.4103/ijph.IJPH_944_20Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern IndiaDivya ValechaP. V. M. LakshmiNaresh SachdevaRajesh KumarBackground: Fetal origin of cardiovascular diseases (CVD) hypothesis has been explored mostly in retrospective studies. Objectives: A prospective study was conducted to find the association of birth weight with CVD risk factors. Methods: A cohort of 243 babies born in 1992–1993 in ten villages of Raipur Rani Block in India, were followed-up in 2016–2017. WHO STEPS methods were used to assess the risk factors of CVDs. A total of 213 (87.8%) participants were examined; blood samples were collected from 207. Multivariable regression analysis was done to adjust for the confounding variables. Results: Study participants were 22–24 year old, 27.7% were exposed to tobacco and 24.8% consumed alcohol, 3.3% were taking >5 servings of fruits and vegetables per day, 35.7% were physically inactive, 28.6% were overweight (body mass index [BMI] ≥23 kg/m2), 12.2% had hypertension, 16% had high cholesterol (≥200 mg/dl), 16.4% had insulin resistance (IR) (Homeostatic Model Assessment-IR >3), and 20.7% were born with low birth weight (<2.5 kg). Multivariable regression analysis revealed inverse relationship between birth weight and systolic blood pressure (regression coefficient ‒3.72 mmHg, 95% confidence interval ‒7.249; ‒0.183, P < 0.05). Conclusion: Birth weight has inverse relationship with blood pressure. Effect of birth weight on CVDs should also be studied in future follow-ups.http://www.ijph.in/article.asp?issn=0019-557X;year=2022;volume=66;issue=1;spage=9;epage=14;aulast=Valechablood pressurebody mass indexcardiovascular diseaseslow birth weight |
| spellingShingle | Divya Valecha P. V. M. Lakshmi Naresh Sachdeva Rajesh Kumar Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern India Indian Journal of Public Health blood pressure body mass index cardiovascular diseases low birth weight |
| title | Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern India |
| title_full | Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern India |
| title_fullStr | Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern India |
| title_full_unstemmed | Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern India |
| title_short | Association of birth weight with risk factors of cardiovascular diseases: A birth cohort analysis from a rural area of Northern India |
| title_sort | association of birth weight with risk factors of cardiovascular diseases a birth cohort analysis from a rural area of northern india |
| topic | blood pressure body mass index cardiovascular diseases low birth weight |
| url | http://www.ijph.in/article.asp?issn=0019-557X;year=2022;volume=66;issue=1;spage=9;epage=14;aulast=Valecha |
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