JR14a: A novel antagonist of C3aR attenuates neuroinflammation in cerebral ischemia-reperfusion injury

JR14a: A novel antagonist of C3aR attenuates neuroinflammation in cerebral ischemia-reperfusion injury

Cerebral ischemia-reperfusion injury (CIRI), a prevalent stroke-related complication, can lead to severe brain damage. Inflammation is a crucial factor in CIRI pathogenesis, and the complement component 3a receptor (C3aR) could be a key mediator in the post-CIRI inflammatory cascade. In this study,...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Jiutang Tang, Nueraili Maihemuti, Yu Fang, Junyi Tan, Mengjie Jia, Qinglan Mu, Keli Huang, Hui Gan, Jing Zhao
Format:	Article
Sprog:	English
Udgivet:	Elsevier 2024-07-01
Serier:	Brain Research Bulletin
Fag:	Cerebral ischemia-reperfusion injury (CIRI) JR14a C3aR Inflammation
Online adgang:	http://www.sciencedirect.com/science/article/pii/S0361923024001199

Lignende værker

Real-time monitoring of ONOO⁻ in cerebral ischemia-reperfusion injury mouse models using a hydrazine-based NIR fluorescent probe
af: Jinting Shang, et al.
Udgivet: (2025-03-01)

Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cerebral Ischemia/Reperfusion Injury
af: Lei Wang, et al.
Udgivet: (2022-05-01)

Study on the mechanism of Wnt/β-catenin pathway mediated by pterostilbene to reduce cerebral ischemia-reperfusion injury
af: Yang Jin, et al.
Udgivet: (2025-02-01)

JrATHB-12 mediates JrMYB113 and JrMYB27 to control the anthocyanin levels in different types of red walnut
af: Haifeng Xu, et al.
Udgivet: (2024-08-01)

Labile Heme Aggravates Renal Inflammation and Complement Activation After Ischemia Reperfusion Injury
af: Li Wang, et al.
Udgivet: (2019-12-01)

Novel insight into the therapeutical potential of flavonoids from traditional Chinese medicine against cerebral ischemia/reperfusion injury
af: Jing Zhou, et al.
Udgivet: (2024-02-01)

Combined Therapy of A<sub>1</sub>AR Agonists and A<sub>2A</sub>AR Antagonists in Neuroinflammation
af: Gabriella Marucci, et al.
Udgivet: (2021-02-01)

CIRI-CIRI PENGERTIAN PETANI KECIL
af: Suproyo Suproyo
Udgivet: (2016-12-01)

Interview: Olival Freire Jr
af: Olival Freira Jr, et al.
Udgivet: (2018-06-01)

Role of traditional Chinese medicine monomers in cerebral ischemia/reperfusion injury:a review of the mechanism
af: Ting Zheng, et al.
Udgivet: (2023-08-01)

Gen inhibiting the Wnt/Ca2+ signaling pathway alleviates cerebral ischemia/reperfusion injury
af: Li Li, et al.
Udgivet: (2025-02-01)

Electroacupuncture reverses endothelial cell death and promotes angiogenesis through the VEGF/Notch signaling pathway after focal cerebral ischemia‐reperfusion injury
af: Wenyu Zhang, et al.
Udgivet: (2023-03-01)

The “C3aR Antagonist” SB290157 is a Partial C5aR2 Agonist
af: Xaria X. Li, et al.
Udgivet: (2021-01-01)

Menjaga Kebugaran Jasmani Sebagai Antisipasi Tertular Virus Corona
af: Aldi Putra, et al.
Udgivet: (2021-08-01)

J.R. Léveillé. Suite
af: Guy Gauthier
Udgivet: (2023-12-01)

Lactiplantibacillus plantarum AR113 alleviates microbiota dysbiosis of tongue coating and cerebral ischemia/reperfusion injury in rat
af: Zhiqiang Xiong, et al.
Udgivet: (2024-07-01)

Puerarin inhibited oxidative stress and alleviated cerebral ischemia-reperfusion injury through PI3K/Akt/Nrf2 signaling pathway
af: Qianqian Zhang, et al.
Udgivet: (2023-05-01)

Léveillé, J.R. Sondes : essais et entrevues
af: Pauline Brise
Udgivet: (2015-05-01)

Léveillé, J.R. Sondes : essais et entrevues
af: Pauline Brise
Udgivet: (2015-05-01)

Analisis Kata Pikat dalam Media Sosial: Satu kajian Semantik
af: Nurul Azyan Zunaidi, et al.
Udgivet: (2021-06-01)

Leonard C. Ferrington, Jr. (1948-2021): Chironomid cognoscente and modern-day Renaissance man
af: Raymond Bouchard, et al.
Udgivet: (2021-12-01)

Léveillé, J.R. Poème pierre prière
af: Swann Paradis
Udgivet: (2012-05-01)

Léveillé, J.R. Poème pierre prière
af: Swann Paradis
Udgivet: (2012-05-01)

Neuroprotective effects of phenylacetylglycine via β2AR on cerebral ischemia/reperfusion injury in rats
af: Wenjie Hu, et al.
Udgivet: (2024-12-01)

Anos 1960: Caio Prado Jr. e "A Revolução Brasileira"
af: José Carlos Reis
Udgivet: (1999-09-01)

Mesenchymal stem cell-derived extracellular vesicles attenuate ferroptosis in aged hepatic ischemia/reperfusion injury by transferring miR-1275
af: Yihang Gong, et al.
Udgivet: (2025-04-01)

Adenosine Receptors as Neuroinflammation Modulators: Role of A<sub>1</sub> Agonists and A<sub>2A</sub> Antagonists
af: Aleix Martí Navia, et al.
Udgivet: (2020-07-01)

EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway
af: Li Wang, et al.
Udgivet: (2022-09-01)

Pembandingan Tiga Nada Vokal /e/ untuk Animasi Gerak Bibir
af: Anung Rachman, et al.
Udgivet: (2019-08-01)

Overcoming high level adenosine-mediated immunosuppression by DZD2269, a potent and selective A2aR antagonist
af: Yu Bai, et al.
Udgivet: (2022-10-01)

The mitochondria as a potential therapeutic target in cerebral I/R injury
af: Susu Fang, et al.
Udgivet: (2025-01-01)

QUEER SCRAPSCAPE: HUDINILSON JR.’S CADERNOS DE REFERÊNCIAS
af: Simone Rossi, et al.
Udgivet: (2023-05-01)

A Escola Austríaca no pensamento de Donald Stewart Jr.
af: Lucas Berlanza Corrêa
Udgivet: (2021-04-01)

Entrevista con Ralph Lee Woodward Jr.
af: Aharon Arguedas Zamora
Udgivet: (2017-04-01)

Dexmedetomidine Alleviates Ischemia/Reperfusion-Associated Acute Kidney Injury by Enhancing Autophagic Activity via the α2-AR/AMPK/mTOR Pathway
af: Bi-Ying Zhou, et al.
Udgivet: (2023-12-01)

Entrevista de Alfredo Pereira Jr.
af: Alfredo Pereira Jr., et al.
Udgivet: (2024-11-01)

The Absence of Madness: Altered States in James Tiptree, Jr.’s Short Fiction
af: Elizabeth Oakes
Udgivet: (2018-06-01)

Reception of John V. A. Fine Jr.’s The Bosnian Church: A New Interpretation: Interesting Sleeve of a Never Ending Historiographical Debate
af: Dzenan Dautovic
Udgivet: (2022-10-01)

Effect of Renal Ischemia Reperfusion on Brain Neuroinflammation
af: Bina Lee, et al.
Udgivet: (2022-11-01)

Model Kejayaan Sistem Maklumat dalam Pengurusan Organisasi
af: Razana Baharudin
Udgivet: (2016-12-01)