JR14a: A novel antagonist of C3aR attenuates neuroinflammation in cerebral ischemia-reperfusion injury
Cerebral ischemia-reperfusion injury (CIRI), a prevalent stroke-related complication, can lead to severe brain damage. Inflammation is a crucial factor in CIRI pathogenesis, and the complement component 3a receptor (C3aR) could be a key mediator in the post-CIRI inflammatory cascade. In this study,...
Main Authors: | Jiutang Tang, Nueraili Maihemuti, Yu Fang, Junyi Tan, Mengjie Jia, Qinglan Mu, Keli Huang, Hui Gan, Jing Zhao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-07-01
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Series: | Brain Research Bulletin |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923024001199 |
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