JR14a: A novel antagonist of C3aR attenuates neuroinflammation in cerebral ischemia-reperfusion injury

JR14a: A novel antagonist of C3aR attenuates neuroinflammation in cerebral ischemia-reperfusion injury

Cerebral ischemia-reperfusion injury (CIRI), a prevalent stroke-related complication, can lead to severe brain damage. Inflammation is a crucial factor in CIRI pathogenesis, and the complement component 3a receptor (C3aR) could be a key mediator in the post-CIRI inflammatory cascade. In this study,...

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Detalles Bibliográficos
Main Authors: Jiutang Tang, Nueraili Maihemuti, Yu Fang, Junyi Tan, Mengjie Jia, Qinglan Mu, Keli Huang, Hui Gan, Jing Zhao
Formato: Artigo
Idioma:English
Publicado: Elsevier 2024-07-01
Series:Brain Research Bulletin
Subjects:
Cerebral ischemia-reperfusion injury (CIRI)
JR14a
C3aR
Inflammation
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0361923024001199

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