Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based Study
Objectives:To study the frequency of diabetes in patients with active pulmonary tuberculosis.To determine the impact of diabetes on radiological findings in tuberculosis.To study the association of atypical radiological manifestations with glycemic control in diabetes associated tuberculosis. Study...
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| Format: | Article |
| Language: | English |
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Riphah International University, Islamabad
2016-06-01
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| Series: | Journal of Islamic International Medical College |
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| Online Access: | https://journals.riphah.edu.pk/index.php/jiimc/article/view/946 |
| _version_ | 1828096627605241856 |
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| author | Shamaila Burney , Omer Awwab Khan , Saerah Iffat Zafar |
| author_facet | Shamaila Burney , Omer Awwab Khan , Saerah Iffat Zafar |
| author_sort | Shamaila Burney , Omer Awwab Khan , Saerah Iffat Zafar |
| collection | DOAJ |
| description | Objectives:To study the frequency of diabetes in patients with active pulmonary tuberculosis.To determine the impact of diabetes on radiological findings in tuberculosis.To study the association of atypical radiological manifestations with glycemic control in diabetes associated tuberculosis.
Study Design: A Descriptive study.
Place and Duration of Study: The study was conducted in Medical Department of Pakistan Air Force Hospital Mianwali from August 2013 to July 2014.
Materials and Methods: Seventy five new cases (18 years and above) of active pulmonary tuberculosis were selected by non-consecutive convenient sampling. All patients received standard anti-tuberculous treatment (ATT) for six months. Fasting blood glucose and chest X-ray were performed in all patients. Glycosylated hemoglobin (HbA1c levels) were checked to assess the glycemic control in diabetic patients. Radiographic features of the two groups; diabetic vs. non diabetic and within diabetic population; poor vs. optimal glycemic control, were then compared.
Results: Thirty three (33/75 or 44%) patients were found to be diabetic. Radiological changes were more frequently atypical in diabetic group as compared to non diabetic population (21/33 or 63.6% vs. 8/42 or 19%). Nine of the 12 diabetic patients with poor glycemic control i.e. HbA1c levels >7% had cavitations, lower zone involvement and bilateral changes as compared to 11/21 patients with optimal glucose control i.e. HbA1c <7% and the difference was significant (9/12 or75% vs.11 /21 or 52.3%, p value <0.001).
Conclusion: A high index of suspicion for diagnosis of diabetes is required for TB patients with atypical radiologicalmanifestations. Poor glycemic control is related with atypical findings on chest X-ray in pulmonary tuberculosis. |
| first_indexed | 2024-04-11T07:33:19Z |
| format | Article |
| id | doaj.art-a9103fd720714eb5bd0af473421f7703 |
| institution | Directory Open Access Journal |
| issn | 1815-4018 2410-5422 |
| language | English |
| last_indexed | 2024-04-11T07:33:19Z |
| publishDate | 2016-06-01 |
| publisher | Riphah International University, Islamabad |
| record_format | Article |
| series | Journal of Islamic International Medical College |
| spelling | doaj.art-a9103fd720714eb5bd0af473421f77032022-12-22T04:36:49ZengRiphah International University, IslamabadJournal of Islamic International Medical College1815-40182410-54222016-06-0111252561342Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based StudyShamaila Burney , Omer Awwab Khan , Saerah Iffat ZafarObjectives:To study the frequency of diabetes in patients with active pulmonary tuberculosis.To determine the impact of diabetes on radiological findings in tuberculosis.To study the association of atypical radiological manifestations with glycemic control in diabetes associated tuberculosis. Study Design: A Descriptive study. Place and Duration of Study: The study was conducted in Medical Department of Pakistan Air Force Hospital Mianwali from August 2013 to July 2014. Materials and Methods: Seventy five new cases (18 years and above) of active pulmonary tuberculosis were selected by non-consecutive convenient sampling. All patients received standard anti-tuberculous treatment (ATT) for six months. Fasting blood glucose and chest X-ray were performed in all patients. Glycosylated hemoglobin (HbA1c levels) were checked to assess the glycemic control in diabetic patients. Radiographic features of the two groups; diabetic vs. non diabetic and within diabetic population; poor vs. optimal glycemic control, were then compared. Results: Thirty three (33/75 or 44%) patients were found to be diabetic. Radiological changes were more frequently atypical in diabetic group as compared to non diabetic population (21/33 or 63.6% vs. 8/42 or 19%). Nine of the 12 diabetic patients with poor glycemic control i.e. HbA1c levels >7% had cavitations, lower zone involvement and bilateral changes as compared to 11/21 patients with optimal glucose control i.e. HbA1c <7% and the difference was significant (9/12 or75% vs.11 /21 or 52.3%, p value <0.001). Conclusion: A high index of suspicion for diagnosis of diabetes is required for TB patients with atypical radiologicalmanifestations. Poor glycemic control is related with atypical findings on chest X-ray in pulmonary tuberculosis.https://journals.riphah.edu.pk/index.php/jiimc/article/view/946atypical chest x-ray, diabetes, glycemic control, pulmonary tuberculosis. |
| spellingShingle | Shamaila Burney , Omer Awwab Khan , Saerah Iffat Zafar Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based Study Journal of Islamic International Medical College atypical chest x-ray, diabetes, glycemic control, pulmonary tuberculosis. |
| title | Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based Study |
| title_full | Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based Study |
| title_fullStr | Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based Study |
| title_full_unstemmed | Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based Study |
| title_short | Effect of Glycemic Control on Radiological Manifestations of Pulmonary Tuberculosis –A Hospital Based Study |
| title_sort | effect of glycemic control on radiological manifestations of pulmonary tuberculosis a hospital based study |
| topic | atypical chest x-ray, diabetes, glycemic control, pulmonary tuberculosis. |
| url | https://journals.riphah.edu.pk/index.php/jiimc/article/view/946 |
| work_keys_str_mv | AT shamailaburneyomerawwabkhansaerahiffatzafar effectofglycemiccontrolonradiologicalmanifestationsofpulmonarytuberculosisahospitalbasedstudy |