Entropy sorting of single-cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo

Entropy sorting of single-cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo

Summary: A major challenge in single-cell gene expression analysis is to discern meaningful cellular heterogeneity from technical or biological noise. To address this challenge, we present entropy sorting (ES), a mathematical framework that distinguishes genes indicative of cell identity. ES achieve...

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Bibliographic Details
Main Authors: Arthur Radley, Elena Corujo-Simon, Jennifer Nichols, Austin Smith, Sara-Jane Dunn
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Stem Cell Reports
Subjects:
single-cell RNA sequencing
feature selection
human embryo inner cell mass
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671122004568

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