Functional Linkage of RKIP to the Epithelial to Mesenchymal Transition and Autophagy during the Development of Prostate Cancer

Functional Linkage of RKIP to the Epithelial to Mesenchymal Transition and Autophagy during the Development of Prostate Cancer

Raf kinase inhibitor protein (RKIP) plays a critical role in many signaling pathways as a multi-functional adapter protein. In particular, the loss of RKIP’s function in certain types of cancer cells results in epithelial to mesenchymal transition (EMT) and the promotion of cancer metastas...

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Bibliographic Details
Main Authors: Mahmoud Ahmed, Trang Huyen Lai, Sahib Zada, Jin Seok Hwang, Trang Minh Pham, Miyong Yun, Deok Ryong Kim
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cancers
Subjects:
RKIP
PEBP1
autophagy
EMT
cancer
microarrays
TCGA
WGCNA
Online Access:http://www.mdpi.com/2072-6694/10/8/273

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