Impaired microvascular reactivity in patients treated with 5-fluorouracil chemotherapy regimens: Potential role of endothelial dysfunction

Impaired microvascular reactivity in patients treated with 5-fluorouracil chemotherapy regimens: Potential role of endothelial dysfunction

Background: 5-fluorouracil (5-FU) is the second most common cancer chemotherapy associated with short- and long-term cardiotoxicity. Although the mechanisms mediating these toxicities are not well understood, patients often present with symptoms suggestive of microvascular dysfunction. We tested the...

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Bibliographic Details
Main Authors: Stephen T. Hammond, Dryden R. Baumfalk, Shannon K. Parr, Alec L.E. Butenas, Britton C. Scheuermann, Vanessa-Rose G. Turpin, Bradley J. Behnke, Mehmood H. Hashmi, Carl J. Ade
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Cardiology: Heart & Vasculature
Subjects:
Cardiotoxicity
Cardio-oncology
Microcirculation
Endothelium
5-fluorouracil
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906723001318

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