A Modular Chain Bioreactor Design for Fungal Productions

Plastic bag bioreactors are single-use bioreactors, frequently used in solid culture fermentation. This study developed plastic bag bioreactors with more effective aeration conditions and particular connection elements that yield sensors, environmental control, and modular connectivity. This bioreac...

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Main Authors: Onur Kırdök, Berker Çetintaş, Asena Atay, İrem Kale, Tutku Didem Akyol Altun, Elif Esin Hameş
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomimetics
Subjects:
Online Access:https://www.mdpi.com/2313-7673/7/4/179
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author Onur Kırdök
Berker Çetintaş
Asena Atay
İrem Kale
Tutku Didem Akyol Altun
Elif Esin Hameş
author_facet Onur Kırdök
Berker Çetintaş
Asena Atay
İrem Kale
Tutku Didem Akyol Altun
Elif Esin Hameş
author_sort Onur Kırdök
collection DOAJ
description Plastic bag bioreactors are single-use bioreactors, frequently used in solid culture fermentation. This study developed plastic bag bioreactors with more effective aeration conditions and particular connection elements that yield sensors, environmental control, and modular connectivity. This bioreactor system integrates the bags in a chain that circulates air and moisture through filtered connections. Within the present scope, this study also aimed to reveal that cultures in different plastic bags can be produced without affecting each other. In this direction, biomass production in the modular chain bioreactor (MCB) system developed in this study was compared to traditional bag systems. In addition, contamination experiments were carried out between the bags in the system, and it was observed that the filters in the developed system did not affect the microorganisms in different bags.
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spelling doaj.art-a92797a2344b4d62a0074de391ef5d1f2023-11-24T13:30:58ZengMDPI AGBiomimetics2313-76732022-10-017417910.3390/biomimetics7040179A Modular Chain Bioreactor Design for Fungal ProductionsOnur Kırdök0Berker Çetintaş1Asena Atay2İrem Kale3Tutku Didem Akyol Altun4Elif Esin Hameş5Department of Biotechnology, Graduate School of Natural and Applied Sciences, Ege University, 35040 İzmir, TürkiyeDepartment of Bioengineering, Graduate School of Natural and Applied Sciences, Ege University, 35040 İzmir, TürkiyeDepartment of Bioengineering, Graduate School of Natural and Applied Sciences, Ege University, 35040 İzmir, TürkiyeDepartment of Architecture, Faculty of Architecture, Dokuz Eylül University, 35390 İzmir, TürkiyeDepartment of Architecture, Faculty of Architecture, Dokuz Eylül University, 35390 İzmir, TürkiyeDepartment of Biotechnology, Graduate School of Natural and Applied Sciences, Ege University, 35040 İzmir, TürkiyePlastic bag bioreactors are single-use bioreactors, frequently used in solid culture fermentation. This study developed plastic bag bioreactors with more effective aeration conditions and particular connection elements that yield sensors, environmental control, and modular connectivity. This bioreactor system integrates the bags in a chain that circulates air and moisture through filtered connections. Within the present scope, this study also aimed to reveal that cultures in different plastic bags can be produced without affecting each other. In this direction, biomass production in the modular chain bioreactor (MCB) system developed in this study was compared to traditional bag systems. In addition, contamination experiments were carried out between the bags in the system, and it was observed that the filters in the developed system did not affect the microorganisms in different bags.https://www.mdpi.com/2313-7673/7/4/179modular chain bioreactorsolid-state fermentationmycelium production<i>Ganoderma lucidum</i>
spellingShingle Onur Kırdök
Berker Çetintaş
Asena Atay
İrem Kale
Tutku Didem Akyol Altun
Elif Esin Hameş
A Modular Chain Bioreactor Design for Fungal Productions
Biomimetics
modular chain bioreactor
solid-state fermentation
mycelium production
<i>Ganoderma lucidum</i>
title A Modular Chain Bioreactor Design for Fungal Productions
title_full A Modular Chain Bioreactor Design for Fungal Productions
title_fullStr A Modular Chain Bioreactor Design for Fungal Productions
title_full_unstemmed A Modular Chain Bioreactor Design for Fungal Productions
title_short A Modular Chain Bioreactor Design for Fungal Productions
title_sort modular chain bioreactor design for fungal productions
topic modular chain bioreactor
solid-state fermentation
mycelium production
<i>Ganoderma lucidum</i>
url https://www.mdpi.com/2313-7673/7/4/179
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