Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism

Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism

The ventricular-subventricular zone (V-SVZ) of the forebrain is the source of neurogenic stem/precursor cells for adaptive and homeostatic needs throughout the life of most mammals. Here, we report that Suppressor of Fused (Sufu) plays a critical role in the establishment of the V-SVZ at early neona...

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Bibliographic Details
Main Authors: Hector G. Gomez, Hirofumi Noguchi, Jesse Garcia Castillo, David Aguilar, Samuel J. Pleasure, Odessa R. Yabut
Format: Article
Language:English
Published: The Company of Biologists 2019-06-01
Series:Biology Open
Subjects:
Neurogenesis
Proliferation
Ventricular-subventricular zone
V-SVZ
Sufu
Gli3
Online Access:http://bio.biologists.org/content/8/6/bio039248

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