Methamphetamine Dysregulates Macrophage Functions and Autophagy to Mediate HIV Neuropathogenesis
HIV-neurocognitive impairment (HIV-NCI) can be a debilitating condition for people with HIV (PWH), despite the success of antiretroviral therapy (ART). Substance use disorder is often a comorbidity with HIV infection. The use of methamphetamine (meth) increases systemic inflammation and CNS damage i...
Main Authors: | John M. Barbaro, Simone Sidoli, Ana Maria Cuervo, Joan W. Berman |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-05-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/10/6/1257 |
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