A general highly efficient synthesis of biocompatible rhodamine dyes and probes for live-cell multicolor nanoscopy

Rhodamines are privileged fluorescent dyes for labelling intracellular structures in living cells. Here, the authors present a facile protecting-group-free synthesis permitting generation of a wide range of symmetrical and unsymmetrical 4-carboxyrhodamines covering the whole visible spectrum.

Bibliographic Details
Main Authors: Jonas Bucevičius, Rūta Gerasimaitė, Kamila A. Kiszka, Shalini Pradhan, Georgij Kostiuk, Tanja Koenen, Gražvydas Lukinavičius
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36913-2