The chromatin remodelling factor Chd7 protects auditory neurons and sensory hair cells from stress-induced degeneration
To improve our understanding of the mechanisms that protect hair cells in the ear from stress-induced death, Ahmed et al delete the chromodomain helicase DNA-binding protein 7 (CHD7) in auditory neurons and hair cells in mice. They observe sensorineural hearing loss and demonstrate that CHD7 control...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02788-6 |