Chitosan-sodium lauryl sulfate/Eudragit S100 beads loaded with 5-fluorouracil: Influence of solvent and duration of crosslinking the crosslinking on physicochemical properties

Chitosan-sodium lauryl sulfate/Eudragit S100 beads loaded with 5-fluorouracil: Influence of solvent and duration of crosslinking the crosslinking on physicochemical properties

Chitosan beads loaded with 5-fluorouracil (5-FU) were prepared by ionotropic gelation using sodium lauryl sulfate (SLS) as a crosslinking agent in presences of Eudragit S100. The objective was to improve the loading and sustained release of 5-FU. The influence of the solvent system, counter ion conc...

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Bibliographic Details
Main Authors: Saravanan Muniyandy, Lui Mei Yi, Aruna Santhagunam, Lay Hong Chuah
Format: Article
Language:English
Published: IOP Publishing 2020-01-01
Series:Materials Research Express
Subjects:
Chitosan
sodium lauryl sulfate
Eudragit S100
5-fluorouracil
ionotropic gelation
drug loading
Online Access:https://doi.org/10.1088/2053-1591/abc90f

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