Corneal and scleral biomechanics in ophthalmic diseases: An updated review

Corneal and scleral biomechanical properties have important implications in the maintenance of normal ocular morphology and function. The cornea and sclera compose the outermost layer of the eyeball, forming a sphere with a certain degree of intraocular pressure, and are therefore under dynamic load...

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Main Authors: Yan Wang, Huazheng Cao
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Medicine in Novel Technology and Devices
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590093522000273
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author Yan Wang
Huazheng Cao
author_facet Yan Wang
Huazheng Cao
author_sort Yan Wang
collection DOAJ
description Corneal and scleral biomechanical properties have important implications in the maintenance of normal ocular morphology and function. The cornea and sclera compose the outermost layer of the eyeball, forming a sphere with a certain degree of intraocular pressure, and are therefore under dynamic loading conditions. Recently, several major ophthalmic conditions have been shown to be linked to corneal and scleral biomechanical properties, such as ametropia, corneal pathologies, ocular surface disease, and glaucoma. A profound understanding of corneal and scleral biomechanics is essential to clarifying disease pathogenesis, improving diagnostic ability, and developing treatment strategies. This review aims to highlight the role of corneal and scleral biomechanics in ophthalmology and its clinical translation. Specifically, advances and prospects in corneal and scleral biomechanics and possible associated diseases are addressed.
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spelling doaj.art-a93378c9c02047178eb9474a268f30832022-12-22T02:25:10ZengElsevierMedicine in Novel Technology and Devices2590-09352022-09-0115100140Corneal and scleral biomechanics in ophthalmic diseases: An updated reviewYan Wang0Huazheng Cao1Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China; Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital, Tianjin, China; Corresponding author. Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Nankai University, Affiliated Eye Hospital No 4. Gansu Road, He-ping District, Tianjin, 300020, China.Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaCorneal and scleral biomechanical properties have important implications in the maintenance of normal ocular morphology and function. The cornea and sclera compose the outermost layer of the eyeball, forming a sphere with a certain degree of intraocular pressure, and are therefore under dynamic loading conditions. Recently, several major ophthalmic conditions have been shown to be linked to corneal and scleral biomechanical properties, such as ametropia, corneal pathologies, ocular surface disease, and glaucoma. A profound understanding of corneal and scleral biomechanics is essential to clarifying disease pathogenesis, improving diagnostic ability, and developing treatment strategies. This review aims to highlight the role of corneal and scleral biomechanics in ophthalmology and its clinical translation. Specifically, advances and prospects in corneal and scleral biomechanics and possible associated diseases are addressed.http://www.sciencedirect.com/science/article/pii/S2590093522000273CorneaScleraBiomechanicsMyopiaGlaucomaIntraocular pressure
spellingShingle Yan Wang
Huazheng Cao
Corneal and scleral biomechanics in ophthalmic diseases: An updated review
Medicine in Novel Technology and Devices
Cornea
Sclera
Biomechanics
Myopia
Glaucoma
Intraocular pressure
title Corneal and scleral biomechanics in ophthalmic diseases: An updated review
title_full Corneal and scleral biomechanics in ophthalmic diseases: An updated review
title_fullStr Corneal and scleral biomechanics in ophthalmic diseases: An updated review
title_full_unstemmed Corneal and scleral biomechanics in ophthalmic diseases: An updated review
title_short Corneal and scleral biomechanics in ophthalmic diseases: An updated review
title_sort corneal and scleral biomechanics in ophthalmic diseases an updated review
topic Cornea
Sclera
Biomechanics
Myopia
Glaucoma
Intraocular pressure
url http://www.sciencedirect.com/science/article/pii/S2590093522000273
work_keys_str_mv AT yanwang cornealandscleralbiomechanicsinophthalmicdiseasesanupdatedreview
AT huazhengcao cornealandscleralbiomechanicsinophthalmicdiseasesanupdatedreview