Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetes
Objective: We analyzed two cohorts of people with type 2 diabetes to evaluate the relationships between depression, sleep quality, and history of hypoglycemia. Research design and methods: Two adult cohorts from Chicago (n = 193) and Bangkok, Thailand (n = 282) with type 2 diabetes completed questio...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-03-01
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| Series: | Journal of Clinical & Translational Endocrinology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214623718301352 |
| _version_ | 1819047947832131584 |
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| author | Alana Biggers Lisa K. Sharp Hataikarn Nimitphong Sunee Saetung Nantaporn Siwasaranond Areesa Manodpitipong Stephanie J. Crowley Megan M. Hood Ben S. Gerber Sirimon Reutrakul |
| author_facet | Alana Biggers Lisa K. Sharp Hataikarn Nimitphong Sunee Saetung Nantaporn Siwasaranond Areesa Manodpitipong Stephanie J. Crowley Megan M. Hood Ben S. Gerber Sirimon Reutrakul |
| author_sort | Alana Biggers |
| collection | DOAJ |
| description | Objective: We analyzed two cohorts of people with type 2 diabetes to evaluate the relationships between depression, sleep quality, and history of hypoglycemia. Research design and methods: Two adult cohorts from Chicago (n = 193) and Bangkok, Thailand (n = 282) with type 2 diabetes completed questionnaires to assess sleep quality, depressive symptoms, and hypoglycemia frequency. Proportional odds logistic regression models for each cohort adjusted for duration of therapy, insulin and sulfonylurea management, and other factors. Results: Those with hypoglycemia in both cohorts had a longer duration of diabetes, greater use of insulin, and worse sleep quality. The Chicago cohort used less sulfonylureas but had higher depressive symptom scores. The Thailand cohort had greater sulfonylurea use. In the final Thailand regression model, depressive symptoms were independently associated with hypoglycemia frequency. In both final Chicago and Thailand models, sleep quality was not associated with hypoglycemia frequency. Conclusions: In the Thailand cohort, depressive symptoms were associated with hypoglycemia frequency. Keywords: Diabetes mellitus, Type 2, Hypoglycemia, Depression, Sleep |
| first_indexed | 2024-12-21T11:08:28Z |
| format | Article |
| id | doaj.art-a9347f7b6343419c9b83dee6ede1e3f3 |
| institution | Directory Open Access Journal |
| issn | 2214-6237 |
| language | English |
| last_indexed | 2024-12-21T11:08:28Z |
| publishDate | 2019-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Clinical & Translational Endocrinology |
| spelling | doaj.art-a9347f7b6343419c9b83dee6ede1e3f32022-12-21T19:06:10ZengElsevierJournal of Clinical & Translational Endocrinology2214-62372019-03-01156264Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetesAlana Biggers0Lisa K. Sharp1Hataikarn Nimitphong2Sunee Saetung3Nantaporn Siwasaranond4Areesa Manodpitipong5Stephanie J. Crowley6Megan M. Hood7Ben S. Gerber8Sirimon Reutrakul9Division of Academic Internal Medicine and Geriatrics, University of Illinois at Chicago, United States; Corresponding author at: Institute for Health Research and Policy (M/C 275), 1747 W. Roosevelt Rd., Chicago, IL 60608, United States.Department of Pharmacy Systems, Outcomes, & Policy, University of Illinois at Chicago, United StatesFaculty of Medicine Ramathibodi Hospital, Mahidol University, ThailandFaculty of Medicine Ramathibodi Hospital, Mahidol University, ThailandFaculty of Medicine Ramathibodi Hospital, Mahidol University, ThailandFaculty of Medicine Ramathibodi Hospital, Mahidol University, ThailandDepartment of Behavioral Sciences, Rush University Medical Center, United StatesDepartment of Behavioral Sciences, Rush University Medical Center, United StatesDivision of Academic Internal Medicine and Geriatrics, University of Illinois at Chicago, United StatesFaculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand; Division of Endocrinology and Metabolism, University of Illinois at Chicago, United StatesObjective: We analyzed two cohorts of people with type 2 diabetes to evaluate the relationships between depression, sleep quality, and history of hypoglycemia. Research design and methods: Two adult cohorts from Chicago (n = 193) and Bangkok, Thailand (n = 282) with type 2 diabetes completed questionnaires to assess sleep quality, depressive symptoms, and hypoglycemia frequency. Proportional odds logistic regression models for each cohort adjusted for duration of therapy, insulin and sulfonylurea management, and other factors. Results: Those with hypoglycemia in both cohorts had a longer duration of diabetes, greater use of insulin, and worse sleep quality. The Chicago cohort used less sulfonylureas but had higher depressive symptom scores. The Thailand cohort had greater sulfonylurea use. In the final Thailand regression model, depressive symptoms were independently associated with hypoglycemia frequency. In both final Chicago and Thailand models, sleep quality was not associated with hypoglycemia frequency. Conclusions: In the Thailand cohort, depressive symptoms were associated with hypoglycemia frequency. Keywords: Diabetes mellitus, Type 2, Hypoglycemia, Depression, Sleephttp://www.sciencedirect.com/science/article/pii/S2214623718301352 |
| spellingShingle | Alana Biggers Lisa K. Sharp Hataikarn Nimitphong Sunee Saetung Nantaporn Siwasaranond Areesa Manodpitipong Stephanie J. Crowley Megan M. Hood Ben S. Gerber Sirimon Reutrakul Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetes Journal of Clinical & Translational Endocrinology |
| title | Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetes |
| title_full | Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetes |
| title_fullStr | Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetes |
| title_full_unstemmed | Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetes |
| title_short | Relationship between depression, sleep quality, and hypoglycemia among persons with type 2 diabetes |
| title_sort | relationship between depression sleep quality and hypoglycemia among persons with type 2 diabetes |
| url | http://www.sciencedirect.com/science/article/pii/S2214623718301352 |
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