بررسی شیوع و الگوی مقاومت آنتی‌بیوتیکی استافیلوکوک‌های کواگولاز منفی در نمونه‌های کراتیت مرتبط با استفاده از لنزهای تماسی

Background: This study aimed to determine the prevalence and antibacterial resistance of coagulase negative staphylococci in keratitis infections after using soft contact lenses in patients admitted at Feiz hospital, Isfahan Iran, in 2013. Methods: In this study, 77 patients with keratitis were exa...

Full description

Bibliographic Details
Main Authors: Golfam Oryan, Jamshid Faghri, Hossein Fazeli, Alireza Zandi, Nafiseh-Sadat Hosseini, Mansour Sedighi, Safora Heidari
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2014-05-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/3521
Description
Summary:Background: This study aimed to determine the prevalence and antibacterial resistance of coagulase negative staphylococci in keratitis infections after using soft contact lenses in patients admitted at Feiz hospital, Isfahan Iran, in 2013. Methods: In this study, 77 patients with keratitis were examined. The samples were cultured and isolation of coagulase negative staphylococcus was done using phenotypic tests and in-vitro sensitivity testing was done using Kirby-Bauer disc diffusion susceptibility method. Findings: 38 isolates were conveniently identified as coagulase negative staphylococci. 27 samples (71.1%) were resistant to penicillin, 21 (55.3%) to erythromycin, and 16 (42.1%), to tetracycline. All the isolates (100%) were sensitive to gentamicin, 36 isolates (94.7%) were sensitive to chloramphenicol, and 33 (86.8%) to ciprofloxacin. Resistance to cefoxitin was seen in 7 (18.4%). Conclusion: Results of this study showed that coagulase negative staphylococci were the most common agents causing contact-lens-related microbial keratitis. In addition, gentamycin, chloramphenicol and ciprofloxacin were more suitable than other antibacterial agents against this type of bacteria.
ISSN:1027-7595
1735-854X