Immunologic risk stratification of pediatric heart transplant patients by combining HLA-EMMA and PIRCHE-II

Immunologic risk stratification of pediatric heart transplant patients by combining HLA-EMMA and PIRCHE-II

Human leukocyte antigen (HLA) molecular mismatch is a powerful biomarker of rejection. Few studies have explored its use in assessing rejection risk in heart transplant recipients. We tested the hypothesis that a combination of HLA Epitope Mismatch Algorithm (HLA-EMMA) and Predicted Indirectly Recog...

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Bibliographic Details
Main Authors: M. Ellison, M. Mangiola, M. Marrari, C. Bentlejewski, J. Sadowski, D. Zern, Cynthia Silvia Maria Kramer, S. Heidt, M. Niemann, Q. Xu, A. I. Dipchand, W. T. Mahle, J. W. Rossano, C. E. Canter, T. P. Singh, W. A. Zuckerman, D. T. Hsu, B. Feingold, S. A. Webber, A. Zeevi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
PIRCHE-II
HLA-EMMA
donor specific antibody
antibody mediated rejection (ABMR)
pediatric heart transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1110292/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1110292/full

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