Estrogen Modulates Glycerol Permeability in Sertoli Cells through Downregulation of Aquaporin-9

Estrogen Modulates Glycerol Permeability in Sertoli Cells through Downregulation of Aquaporin-9

High 17β-Estradiol (E2) levels are known to cause alterations of spermatogenesis and environments throughout the male reproductive tract. Sertoli cells (SCs) ensure an adequate environment inside the seminiferous tubule. Glycerol stands as essential for the maintenance of blood–te...

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Bibliographic Details
Main Authors: Raquel L. Bernardino, David F. Carrageta, Ana M. Silva, Giuseppe Calamita, Marco G. Alves, Graça Soveral, Pedro F. Oliveira
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Cells
Subjects:
aquaglyceroporins
AQP9
estrogens
glycerol
male infertility
Sertoli cells
Online Access:http://www.mdpi.com/2073-4409/7/10/153

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