Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patient
Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome characterized by excessive macrophage function. The diagnosis of HLH in adults is challenging because initial signs and symptoms of HLH mimic common infections. Herein is described a case of HSV infection causing virus-associated h...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2017-09-01
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Series: | Journal of Cancer Research and Practice |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2311300616301859 |
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author | I-Hsuan Huang Wei-Chun Lin Ping-Ying Chang |
author_facet | I-Hsuan Huang Wei-Chun Lin Ping-Ying Chang |
author_sort | I-Hsuan Huang |
collection | DOAJ |
description | Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome characterized by excessive macrophage function. The diagnosis of HLH in adults is challenging because initial signs and symptoms of HLH mimic common infections. Herein is described a case of HSV infection causing virus-associated hemophagocytic syndrome (VAHS) with severe hemodynamic distress. This patient manifested acute respiratory distress syndrome (ARDS), which responded well to intravenous immunoglobulin. Patients with herpes simplex virus-associated hemophagocytic syndrome coexisting with ARDS may be given a trial of immune globulin. However, there are few reported cases of AML occurring with VAHS in the literature, which were successfully treated with IVIG; therefore, this finding requires further investigation in a similar setting. |
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id | doaj.art-a93cfa8bd43d4f8dbb363920c38e0793 |
institution | Directory Open Access Journal |
issn | 2311-3006 |
language | English |
last_indexed | 2024-04-12T01:37:32Z |
publishDate | 2017-09-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Cancer Research and Practice |
spelling | doaj.art-a93cfa8bd43d4f8dbb363920c38e07932022-12-22T03:53:17ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062017-09-014310911010.1016/j.jcrpr.2017.02.003Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patientI-Hsuan Huang0Wei-Chun Lin1Ping-Ying Chang2Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDepartment of Surgery, Song Shan Branch, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDivision of Hematology Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanHemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome characterized by excessive macrophage function. The diagnosis of HLH in adults is challenging because initial signs and symptoms of HLH mimic common infections. Herein is described a case of HSV infection causing virus-associated hemophagocytic syndrome (VAHS) with severe hemodynamic distress. This patient manifested acute respiratory distress syndrome (ARDS), which responded well to intravenous immunoglobulin. Patients with herpes simplex virus-associated hemophagocytic syndrome coexisting with ARDS may be given a trial of immune globulin. However, there are few reported cases of AML occurring with VAHS in the literature, which were successfully treated with IVIG; therefore, this finding requires further investigation in a similar setting.http://www.sciencedirect.com/science/article/pii/S2311300616301859Hemophagocytic syndromeIntravenous immunoglobulinAcute respiratory distress syndrome |
spellingShingle | I-Hsuan Huang Wei-Chun Lin Ping-Ying Chang Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patient Journal of Cancer Research and Practice Hemophagocytic syndrome Intravenous immunoglobulin Acute respiratory distress syndrome |
title | Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patient |
title_full | Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patient |
title_fullStr | Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patient |
title_full_unstemmed | Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patient |
title_short | Successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ARDS with intravenous immunoglobulin in acute myeloid leukemia patient |
title_sort | successful treatment of herpes simplex virus associated hemophagocytic syndrome coexisting with ards with intravenous immunoglobulin in acute myeloid leukemia patient |
topic | Hemophagocytic syndrome Intravenous immunoglobulin Acute respiratory distress syndrome |
url | http://www.sciencedirect.com/science/article/pii/S2311300616301859 |
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