Cancer Omics in Africa: Present and Prospects
During the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and meta...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2020.606428/full |
| _version_ | 1818594459042971648 |
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| author | Islam El Jaddaoui Imane Allali Sofia Sehli Karim Ouldim Salsabil Hamdi Najib Al Idrissi Chakib Nejjari Saaïd Amzazi Youssef Bakri Hassan Ghazal Hassan Ghazal |
| author_facet | Islam El Jaddaoui Imane Allali Sofia Sehli Karim Ouldim Salsabil Hamdi Najib Al Idrissi Chakib Nejjari Saaïd Amzazi Youssef Bakri Hassan Ghazal Hassan Ghazal |
| author_sort | Islam El Jaddaoui |
| collection | DOAJ |
| description | During the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and metagenomics are the main multi omics strategies used currently in the diagnosis, prognosis, treatment, and biomarker discovery in cancer. In this review, we describe the use of different multi omics strategies in cancer research in the African continent and discuss the main challenges facing the implementation of these approaches in African countries such as the lack of training programs in bioinformatics in general and omics strategies in particular and suggest paths to address deficiencies. As a way forward, we advocate for the establishment of an “African Cancer Genomics Consortium” to promote intracontinental collaborative projects and enhance engagement in research activities that address indigenous aspects for cancer precision medicine. |
| first_indexed | 2024-12-16T11:00:27Z |
| format | Article |
| id | doaj.art-a9407a90bf0a4d1d9b746040a6cc26ad |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-16T11:00:27Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-a9407a90bf0a4d1d9b746040a6cc26ad2022-12-21T22:34:01ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2020-12-011010.3389/fonc.2020.606428606428Cancer Omics in Africa: Present and ProspectsIslam El Jaddaoui0Imane Allali1Sofia Sehli2Karim Ouldim3Salsabil Hamdi4Najib Al Idrissi5Chakib Nejjari6Saaïd Amzazi7Youssef Bakri8Hassan Ghazal9Hassan Ghazal10Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, MoroccoLaboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, MoroccoDepartment of Fundamental Sciences, School of Medicine, Mohammed VI University of Health Sciences, Casablanca, MoroccoCancer Research Institute, Fes, MoroccoEnvironmental Health Laboratory, Pasteur Institute, Casablanca, MoroccoDepartment of Surgery, School of Medicine, Mohammed VI University of Health Sciences, Casablanca, MoroccoDepartment of Medicine, School of Medicine, Mohammed VI University of Health Sciences, Casablanca, MoroccoLaboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, MoroccoLaboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, MoroccoDepartment of Fundamental Sciences, School of Medicine, Mohammed VI University of Health Sciences, Casablanca, MoroccoNational Center for Scientific and Technical Research, Rabat, MoroccoDuring the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and metagenomics are the main multi omics strategies used currently in the diagnosis, prognosis, treatment, and biomarker discovery in cancer. In this review, we describe the use of different multi omics strategies in cancer research in the African continent and discuss the main challenges facing the implementation of these approaches in African countries such as the lack of training programs in bioinformatics in general and omics strategies in particular and suggest paths to address deficiencies. As a way forward, we advocate for the establishment of an “African Cancer Genomics Consortium” to promote intracontinental collaborative projects and enhance engagement in research activities that address indigenous aspects for cancer precision medicine.https://www.frontiersin.org/articles/10.3389/fonc.2020.606428/fullmulti omicscancer genomicsepigenomicstranscriptomicsmetabolomicsproteomics |
| spellingShingle | Islam El Jaddaoui Imane Allali Sofia Sehli Karim Ouldim Salsabil Hamdi Najib Al Idrissi Chakib Nejjari Saaïd Amzazi Youssef Bakri Hassan Ghazal Hassan Ghazal Cancer Omics in Africa: Present and Prospects Frontiers in Oncology multi omics cancer genomics epigenomics transcriptomics metabolomics proteomics |
| title | Cancer Omics in Africa: Present and Prospects |
| title_full | Cancer Omics in Africa: Present and Prospects |
| title_fullStr | Cancer Omics in Africa: Present and Prospects |
| title_full_unstemmed | Cancer Omics in Africa: Present and Prospects |
| title_short | Cancer Omics in Africa: Present and Prospects |
| title_sort | cancer omics in africa present and prospects |
| topic | multi omics cancer genomics epigenomics transcriptomics metabolomics proteomics |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2020.606428/full |
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