Stochastic Model of Virus–Endosome Fusion and Endosomal Escape of pH-Responsive Nanoparticles

Stochastic Model of Virus–Endosome Fusion and Endosomal Escape of pH-Responsive Nanoparticles

In this paper, we set up a stochastic model for the dynamics of active Rab5 and Rab7 proteins on the surface of endosomes and the acidification process that govern the virus–endosome fusion and endosomal escape of pH-responsive nanoparticles. We employ a well-known cut-off switch model for Rab5 to R...

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Bibliographic Details
Main Authors: Sergei Fedotov, Dmitri Alexandrov, Ilya Starodumov, Nickolay Korabel
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Mathematics
Subjects:
stochastic ODE’s
virus–endosome fusion
endosomal escape
viruses
pH-responsive nanoparticles
Online Access:https://www.mdpi.com/2227-7390/10/3/375

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