A bidirectional Mendelian randomization study about the role of morning plasma cortisol in attention deficit hyperactivity disorder

A bidirectional Mendelian randomization study about the role of morning plasma cortisol in attention deficit hyperactivity disorder

ContextCortisol, a hormone regulated by the hypothalamic-pituitary-adrenal (HPA) axis, has been linked to attention deficit hyperactivity disorder (ADHD). The nature of the relationship between cortisol and ADHD, and whether it is causal or explained by reverse causality, remains a matter of debate....

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Bibliographic Details
Main Authors: Hu Jue, Li Fang-fang, Chen Dan-fei, Chen Nuo, Ye Chun-lu, Yu Ke-pin, Chen Jian, Xuan Xiao-bo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Psychiatry
Subjects:
cortisol
Mendelian randomization
attention deficit hyperactivity disorder
hypothalamic-pituitary-adrenal
single-nucleotide polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1148759/full

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