The genome of tolypocladium inflatum: evolution, organization, and expression of the cyclosporin biosynthetic gene cluster.

The genome of tolypocladium inflatum: evolution, organization, and expression of the cyclosporin biosynthetic gene cluster.

The ascomycete fungus Tolypocladium inflatum, a pathogen of beetle larvae, is best known as the producer of the immunosuppressant drug cyclosporin. The draft genome of T. inflatum strain NRRL 8044 (ATCC 34921), the isolate from which cyclosporin was first isolated, is presented along with comparativ...

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Main Authors: Kathryn E Bushley, Rajani Raja, Pankaj Jaiswal, Jason S Cumbie, Mariko Nonogaki, Alexander E Boyd, C Alisha Owensby, Brian J Knaus, Justin Elser, Daniel Miller, Yanming Di, Kerry L McPhail, Joseph W Spatafora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3688495?pdf=render

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