Progress in the biological function of alpha-enolase

Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections...

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Bibliographic Details
Main Authors: Hong Ji, Jianfa Wang, Jingru Guo, Yue Li, Shuai Lian, Wenjin Guo, Huanmin Yang, Fanzhi Kong, Li Zhen, Li Guo, Yanzhi Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2016-03-01
Series:Animal Nutrition
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405654515300755
Description
Summary:Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections, autoantigen activities, the occurrence and metastasis of cancer, parasitic infections, and the growth, development and reproduction of organisms. This article mainly reviews the basic characteristics and biological functions of ENO1.
ISSN:2405-6545