Divergent Effects of miR‐181 Family Members on Myocardial Function Through Protective Cytosolic and Detrimental Mitochondrial microRNA Targets

Divergent Effects of miR‐181 Family Members on Myocardial Function Through Protective Cytosolic and Detrimental Mitochondrial microRNA Targets

Background MicroRNA (miRNA) is a type of noncoding RNA that can repress the expression of target genes through posttranscriptional regulation. In addition to numerous physiologic roles for miRNAs, they play an important role in pathophysiologic processes affecting cardiovascular health. Previously,...

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Bibliographic Details
Main Authors: Samarjit Das, Mark Kohr, Brittany Dunkerly‐Eyring, Dong I. Lee, Djahida Bedja, Oliver A. Kent, Anthony K. L. Leung, Jorge Henao‐Mejia, Richard A. Flavell, Charles Steenbergen
Format: Article
Language:English
Published: Wiley 2017-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
microRNA
miR‐181
mitochondria
mitochondrial miRNA
mitochondrial respiratory complex IV
mt‐COX1
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004694

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