Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria

Background: Nursing home residents often have several conditions that necessitate the use of multiple medicines. This study investigates the prevalence of potentially inappropriate medications (PIMs) and its associations with sex, age, number of medicines, and study location (rural/urban). Methods:...

Full description

Bibliographic Details
Main Authors: Kjell H. Halvorsen, Sinan Kucukcelik, Beate H. Garcia, Kristian Svendsen
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Pharmacy
Subjects:
Online Access:http://www.mdpi.com/2226-4787/7/1/26
_version_ 1811303521208762368
author Kjell H. Halvorsen
Sinan Kucukcelik
Beate H. Garcia
Kristian Svendsen
author_facet Kjell H. Halvorsen
Sinan Kucukcelik
Beate H. Garcia
Kristian Svendsen
author_sort Kjell H. Halvorsen
collection DOAJ
description Background: Nursing home residents often have several conditions that necessitate the use of multiple medicines. This study investigates the prevalence of potentially inappropriate medications (PIMs) and its associations with sex, age, number of medicines, and study location (rural/urban). Methods: A cross-sectional study of long-term care residents from six nursing homes. Data was collected from medical records. We identified PIMs by applying the NORGEP-NH criteria. We conducted a Poisson regression analysis to investigate the association between the number of PIMs and sex, age, number of medicines, and study location. Results: We included 103 (18.4%) of 559 residents (68.0% women; mean age 83.2 years, mean number of daily used medicines 7.2 (SD = 3.6)). We identified PIMs in 56% of the residents (mean number = 1.10, SD = 1.26). In adjusted analyses, residents ≥80 years had 0.43 fewer PIMs compared to residents <80 years (p < 0.05). Residents using 4–6, 7–9, and 10+ medicines had on average 0.73, 1.06, and 2.11 more PIMs compared to residents using 0–3 medicines (p < 0.001), respectively. Conclusion: PIM use is prevalent among nursing home residents and is significantly associated with age and number of medicines. Our findings suggest a modest decrease in residents using PIMs compared to previous studies. Nevertheless, prescribing quality in nursing home residents in both urban and rural areas is still of great concern.
first_indexed 2024-04-13T07:49:22Z
format Article
id doaj.art-a94f9a3084264f2ea505ddf96bbce381
institution Directory Open Access Journal
issn 2226-4787
language English
last_indexed 2024-04-13T07:49:22Z
publishDate 2019-03-01
publisher MDPI AG
record_format Article
series Pharmacy
spelling doaj.art-a94f9a3084264f2ea505ddf96bbce3812022-12-22T02:55:35ZengMDPI AGPharmacy2226-47872019-03-01712610.3390/pharmacy7010026pharmacy7010026Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH CriteriaKjell H. Halvorsen0Sinan Kucukcelik1Beate H. Garcia2Kristian Svendsen3Department of Pharmacy, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø N-9037, NorwayDepartment of Pharmacy, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø N-9037, NorwayDepartment of Pharmacy, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø N-9037, NorwayDepartment of Pharmacy, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø N-9037, NorwayBackground: Nursing home residents often have several conditions that necessitate the use of multiple medicines. This study investigates the prevalence of potentially inappropriate medications (PIMs) and its associations with sex, age, number of medicines, and study location (rural/urban). Methods: A cross-sectional study of long-term care residents from six nursing homes. Data was collected from medical records. We identified PIMs by applying the NORGEP-NH criteria. We conducted a Poisson regression analysis to investigate the association between the number of PIMs and sex, age, number of medicines, and study location. Results: We included 103 (18.4%) of 559 residents (68.0% women; mean age 83.2 years, mean number of daily used medicines 7.2 (SD = 3.6)). We identified PIMs in 56% of the residents (mean number = 1.10, SD = 1.26). In adjusted analyses, residents ≥80 years had 0.43 fewer PIMs compared to residents <80 years (p < 0.05). Residents using 4–6, 7–9, and 10+ medicines had on average 0.73, 1.06, and 2.11 more PIMs compared to residents using 0–3 medicines (p < 0.001), respectively. Conclusion: PIM use is prevalent among nursing home residents and is significantly associated with age and number of medicines. Our findings suggest a modest decrease in residents using PIMs compared to previous studies. Nevertheless, prescribing quality in nursing home residents in both urban and rural areas is still of great concern.http://www.mdpi.com/2226-4787/7/1/26nursing home residentspotentially inappropriate medicationsquality of healthpharmacoepidemiologydrug therapyexplicit criteria lists
spellingShingle Kjell H. Halvorsen
Sinan Kucukcelik
Beate H. Garcia
Kristian Svendsen
Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
Pharmacy
nursing home residents
potentially inappropriate medications
quality of health
pharmacoepidemiology
drug therapy
explicit criteria lists
title Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_full Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_fullStr Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_full_unstemmed Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_short Assessing Potentially Inappropriate Medications in Nursing Home Residents by NORGEP-NH Criteria
title_sort assessing potentially inappropriate medications in nursing home residents by norgep nh criteria
topic nursing home residents
potentially inappropriate medications
quality of health
pharmacoepidemiology
drug therapy
explicit criteria lists
url http://www.mdpi.com/2226-4787/7/1/26
work_keys_str_mv AT kjellhhalvorsen assessingpotentiallyinappropriatemedicationsinnursinghomeresidentsbynorgepnhcriteria
AT sinankucukcelik assessingpotentiallyinappropriatemedicationsinnursinghomeresidentsbynorgepnhcriteria
AT beatehgarcia assessingpotentiallyinappropriatemedicationsinnursinghomeresidentsbynorgepnhcriteria
AT kristiansvendsen assessingpotentiallyinappropriatemedicationsinnursinghomeresidentsbynorgepnhcriteria