An unexpected function of the Prader-Willi syndrome imprinting center in maternal imprinting in mice.

Genomic imprinting is a phenomenon that some genes are expressed differentially according to the parent of origin. Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are neurobehavioral disorders caused by deficiency of imprinted gene expression from paternal and maternal chromosome 15q11-q13, r...

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Bibliographic Details
Main Authors: Mei-Yi Wu, Ming Jiang, Xiaodong Zhai, Arthur L Beaudet, Ray-Chang Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3319576?pdf=render