High-Throughput Neutralization and Serology Assays Reveal Correlated but Highly Variable Humoral Immune Responses in a Large Population of Individuals Infected with SARS-CoV-2 in the US between March and August 2020

High-Throughput Neutralization and Serology Assays Reveal Correlated but Highly Variable Humoral Immune Responses in a Large Population of Individuals Infected with SARS-CoV-2 in the US between March and August 2020

ABSTRACT The ability to measure neutralizing antibodies on large scale can be important for understanding features of the natural history and epidemiology of infection, as well as an aid in determining the efficacy of interventions, particularly in outbreaks such as the current severe acute respirat...

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Bibliographic Details
Main Authors: Shuting Zhang, Peijun Ma, Marek Orzechowski, Allison Lemmer, Kara Rzasa, Josephine Bagnall, Sulyman Barkho, Michael Chen, Lorri He, Raymond Neitupski, Victoria Tran, Ross Ackerman, Emily Gath, Austin Bond, Giana Frongillo, Thomas Cleland, Aaron Golas, Anthony Gaca, Michael Fitzgerald, Kathleen Kelly, Kelsey Hazegh, Larry Dumont, Corey Hoffman, Mary Homer, Peter Marks, Ann Woolley, Sharon Wong, James Gomez, Jonathan Livny, Deborah Hung
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mBio
Subjects:
SARS-CoV-2
neutralizing antibodies
serology
Online Access:https://journals.asm.org/doi/10.1128/mbio.03523-22

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