α-smooth muscle actin is not a marker of fibrogenic cell activity in skeletal muscle fibrosis.
α-Smooth muscle actin (α-SMA) is used as a marker for a subset of activated fibrogenic cells, myofibroblasts, which are regarded as important effector cells of tissue fibrogenesis. We address whether α-SMA-expressing myofibroblasts are detectable in fibrotic muscles of mdx5cv mice, a mouse model for...
Main Authors: | Wanming Zhao, Xingyu Wang, Kai-Hui Sun, Lan Zhou |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5761950?pdf=render |
Similar Items
-
α-Smooth Muscle Actin and ACTA2 Gene Expressions in Vasculopathies
by: Shi-Min Yuan
Published: (2015-12-01) -
Increased fibroblast telomerase expression precedes myofibroblast α-smooth muscle actin expression in idiopathic pulmonary fibrosis
by: Daniel Reis Waisberg, et al.
Published: (2012-09-01) -
Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells
by: Nilesh P. Talele, et al.
Published: (2015-06-01) -
An α-smooth muscle actin (acta2/αsma) zebrafish transgenic line marking vascular mural cells and visceral smooth muscle cells.
by: Thomas R Whitesell, et al.
Published: (2014-01-01) -
Immunohistochemical evaluation of myofibroblasts using alpha-smooth muscle actin in oral submucous fibrosis
by: Teena Philip, et al.
Published: (2014-01-01)