<i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning Piglets
<i>Eucommia ulmoides</i> flavones (EUF) have been demonstrated to attenuate the inflammation and oxidative stress of piglets. This study aimed to test whether EUF could be used as an alternative antibiotic growth promoter to support growth performance and maintain intestinal health in we...
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MDPI AG
2020-10-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/10/11/1998 |
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| author | Daixiu Yuan Jing Wang Dingfu Xiao Jiefeng Li Yanhong Liu Bie Tan Yulong Yin |
| author_facet | Daixiu Yuan Jing Wang Dingfu Xiao Jiefeng Li Yanhong Liu Bie Tan Yulong Yin |
| author_sort | Daixiu Yuan |
| collection | DOAJ |
| description | <i>Eucommia ulmoides</i> flavones (EUF) have been demonstrated to attenuate the inflammation and oxidative stress of piglets. This study aimed to test whether EUF could be used as an alternative antibiotic growth promoter to support growth performance and maintain intestinal health in weanling piglets. Weaned piglets (<i>n</i> = 480) were assigned into three groups and fed with a low-protein basal diet (NC), or supplementation with antibiotics (PC) or 0.01% EUF (EUF). Blood, intestinal contents, and intestine were collected on days 15 and 35 after weaning. The results showed the PC and EUF supplementations increased (<i>p</i> < 0.05) body weight on day 35, average daily gain and gain: feed ratio from day 15 to day 35 and day 0 to day 35, whereas decreased (<i>p</i> < 0.05) the diarrhea index of weanling piglets. EUF treatment increased (<i>p</i> < 0.05) jejunal villus height: crypt depth ratio, jejunal and ileal villus height, and population of ileal lactic acid bacteria on day 15 but decreased (<i>p</i> < 0.05) the population of ileal coliform bacteria on day 15 and day 35. These findings indicated the EUF, as the potential alternative to in-feed antibiotic growth promoter, could improve growth performance and intestinal morphology, and decrease colonization of coliform bacteria and diarrhea index in weanling piglets. |
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| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T15:13:13Z |
| publishDate | 2020-10-01 |
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| series | Animals |
| spelling | doaj.art-a956bd3bc4db49008439667996a1778d2023-11-20T19:11:43ZengMDPI AGAnimals2076-26152020-10-011011199810.3390/ani10111998<i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning PigletsDaixiu Yuan0Jing Wang1Dingfu Xiao2Jiefeng Li3Yanhong Liu4Bie Tan5Yulong Yin6Department of Medicine, Jishou University, Jishou 416000, ChinaDepartment of Animal Science, Hunan Agricultural University, Changsha 410000, ChinaDepartment of Animal Science, Hunan Agricultural University, Changsha 410000, ChinaLaboratory of Animal Nutritional Physiology and Metabolic Processes, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Key Laboratory of Agroecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, ChinaDepartment of Animal Science, University of California, Davis, CA 95616, USADepartment of Animal Science, Hunan Agricultural University, Changsha 410000, ChinaLaboratory of Animal Nutritional Physiology and Metabolic Processes, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Key Laboratory of Agroecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China<i>Eucommia ulmoides</i> flavones (EUF) have been demonstrated to attenuate the inflammation and oxidative stress of piglets. This study aimed to test whether EUF could be used as an alternative antibiotic growth promoter to support growth performance and maintain intestinal health in weanling piglets. Weaned piglets (<i>n</i> = 480) were assigned into three groups and fed with a low-protein basal diet (NC), or supplementation with antibiotics (PC) or 0.01% EUF (EUF). Blood, intestinal contents, and intestine were collected on days 15 and 35 after weaning. The results showed the PC and EUF supplementations increased (<i>p</i> < 0.05) body weight on day 35, average daily gain and gain: feed ratio from day 15 to day 35 and day 0 to day 35, whereas decreased (<i>p</i> < 0.05) the diarrhea index of weanling piglets. EUF treatment increased (<i>p</i> < 0.05) jejunal villus height: crypt depth ratio, jejunal and ileal villus height, and population of ileal lactic acid bacteria on day 15 but decreased (<i>p</i> < 0.05) the population of ileal coliform bacteria on day 15 and day 35. These findings indicated the EUF, as the potential alternative to in-feed antibiotic growth promoter, could improve growth performance and intestinal morphology, and decrease colonization of coliform bacteria and diarrhea index in weanling piglets.https://www.mdpi.com/2076-2615/10/11/1998antibiotic alternatives<i>Eucommia ulmoides</i> flavonesgrowth performanceintestinal barrierweaning piglets |
| spellingShingle | Daixiu Yuan Jing Wang Dingfu Xiao Jiefeng Li Yanhong Liu Bie Tan Yulong Yin <i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning Piglets Animals antibiotic alternatives <i>Eucommia ulmoides</i> flavones growth performance intestinal barrier weaning piglets |
| title | <i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning Piglets |
| title_full | <i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning Piglets |
| title_fullStr | <i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning Piglets |
| title_full_unstemmed | <i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning Piglets |
| title_short | <i>Eucommia ulmoides</i> Flavones as Potential Alternatives to Antibiotic Growth Promoters in a Low-Protein Diet Improve Growth Performance and Intestinal Health in Weaning Piglets |
| title_sort | i eucommia ulmoides i flavones as potential alternatives to antibiotic growth promoters in a low protein diet improve growth performance and intestinal health in weaning piglets |
| topic | antibiotic alternatives <i>Eucommia ulmoides</i> flavones growth performance intestinal barrier weaning piglets |
| url | https://www.mdpi.com/2076-2615/10/11/1998 |
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