Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in context
Summary: Objective was to update a clinical practice guideline (CPG) for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients. We reconvened a multi-disciplinary and multi-national panel. While the previous 2018 CPG evaluated adult a...
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-09-01
|
| Series: | EClinicalMedicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589537023003243 |
| _version_ | 1797745136318283776 |
|---|---|
| author | Priya Patel Paula D. Robinson Patrick van der Torre Deborah Tomlinson Jennifer Seelisch Sapna Oberoi Jessica E. Morgan Pamela S. Hinds Miriam Götte Faith Gibson Nathan Duong Hailey Davis S. Nicole Culos-Reed Danielle Cataudella Vanessa Miranda L. Lee Dupuis Lillian Sung |
| author_facet | Priya Patel Paula D. Robinson Patrick van der Torre Deborah Tomlinson Jennifer Seelisch Sapna Oberoi Jessica E. Morgan Pamela S. Hinds Miriam Götte Faith Gibson Nathan Duong Hailey Davis S. Nicole Culos-Reed Danielle Cataudella Vanessa Miranda L. Lee Dupuis Lillian Sung |
| author_sort | Priya Patel |
| collection | DOAJ |
| description | Summary: Objective was to update a clinical practice guideline (CPG) for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients. We reconvened a multi-disciplinary and multi-national panel. While the previous 2018 CPG evaluated adult and pediatric randomized controlled trials (RCTs) to manage fatigue, this 2023 update revised previous recommendations based only on pediatric RCTs. Twenty RCTs were included in the updated systematic review. Physical activity significantly reduced fatigue (standardized mean difference −0.44, 95% confidence interval −0.64 to −0.24; n = 8 RCTs). Using the 2018 recommendations as a basis, the panel continued to make strong recommendations to use physical activity, and to offer relaxation, mindfulness or both, to manage fatigue in pediatric patients. Cognitive or cognitive behavioral therapies may be offered. Pharmacological approaches should not be routinely used. The panel made a new good practice statement to routinely assess for fatigue, ideally using a validated scale. |
| first_indexed | 2024-03-12T15:19:09Z |
| format | Article |
| id | doaj.art-a957b0aa2b12422e906785843838005e |
| institution | Directory Open Access Journal |
| issn | 2589-5370 |
| language | English |
| last_indexed | 2024-03-12T15:19:09Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | EClinicalMedicine |
| spelling | doaj.art-a957b0aa2b12422e906785843838005e2023-08-11T05:35:15ZengElsevierEClinicalMedicine2589-53702023-09-0163102147Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in contextPriya Patel0Paula D. Robinson1Patrick van der Torre2Deborah Tomlinson3Jennifer Seelisch4Sapna Oberoi5Jessica E. Morgan6Pamela S. Hinds7Miriam Götte8Faith Gibson9Nathan Duong10Hailey Davis11S. Nicole Culos-Reed12Danielle Cataudella13Vanessa Miranda14L. Lee Dupuis15Lillian Sung16Pediatric Oncology Group of Ontario, 480 University Ave, Suite 1014, Toronto, ON M5G 1V2, Canada; Department of Pharmacy, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, CanadaPediatric Oncology Group of Ontario, 480 University Ave, Suite 1014, Toronto, ON M5G 1V2, CanadaSport and Exercise Center, Princess Máxima Center for Pediatric Oncology, Utrecht 3584CS, the NetherlandsChild Health Evaluative Sciences, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, CanadaDivision of Hematology/Oncology, Children’s Hospital London Health Sciences Centre, 800 Commissioners Rd E, London, ON N6A 5W9, CanadaDepartment of Pediatrics and Child Health, Max Rady College of Medicine, CancerCare Manitoba, University of Manitoba, 675 McDermot Ave, Winnipeg, MB R3E 0V9, CanadaCentre for Reviews and Dissemination, University of York, York YO10 5DD, UK; Department of Paediatric Haematology and Oncology, Leeds Children's Hospital, Leeds LS1 3EX, UKDepartment of Nursing Science, Professional Practice, and Quality, Children's National Health System, Washington, DC, USA; Department of Pediatrics, George Washington University, 111 Michigan Ave NW, Washington, DC 20010, USAUniversity Hospital Essen, West German Cancer Center, Hufelandstraße 55, Essen 45147, GermanyCentre for Outcomes and Experiences Research in Children's Health, Illness, and Disability, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; School of Health Sciences, University of Surrey, 388 Stag Hill, Guildford GU2 7XH, UKNot Applicable (Patient Representative)Not Applicable (Patient Representative)Faculty of Kinesiology, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, CanadaDepartment of Pediatric Psychology, Children's Hospital, London Health Sciences Centre, 800 Commissioners Rd E, London, ON N6A 5W9, CanadaPediatric Oncology Group of Ontario, 480 University Ave, Suite 1014, Toronto, ON M5G 1V2, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College St, Toronto, ON M5S 3M2, CanadaDepartment of Pharmacy, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada; Child Health Evaluative Sciences, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College St, Toronto, ON M5S 3M2, CanadaChild Health Evaluative Sciences, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada; Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada; Corresponding author. Division of Haematology/Oncology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.Summary: Objective was to update a clinical practice guideline (CPG) for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients. We reconvened a multi-disciplinary and multi-national panel. While the previous 2018 CPG evaluated adult and pediatric randomized controlled trials (RCTs) to manage fatigue, this 2023 update revised previous recommendations based only on pediatric RCTs. Twenty RCTs were included in the updated systematic review. Physical activity significantly reduced fatigue (standardized mean difference −0.44, 95% confidence interval −0.64 to −0.24; n = 8 RCTs). Using the 2018 recommendations as a basis, the panel continued to make strong recommendations to use physical activity, and to offer relaxation, mindfulness or both, to manage fatigue in pediatric patients. Cognitive or cognitive behavioral therapies may be offered. Pharmacological approaches should not be routinely used. The panel made a new good practice statement to routinely assess for fatigue, ideally using a validated scale.http://www.sciencedirect.com/science/article/pii/S2589537023003243Practice guidelineFatiguePediatric oncology |
| spellingShingle | Priya Patel Paula D. Robinson Patrick van der Torre Deborah Tomlinson Jennifer Seelisch Sapna Oberoi Jessica E. Morgan Pamela S. Hinds Miriam Götte Faith Gibson Nathan Duong Hailey Davis S. Nicole Culos-Reed Danielle Cataudella Vanessa Miranda L. Lee Dupuis Lillian Sung Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in context EClinicalMedicine Practice guideline Fatigue Pediatric oncology |
| title | Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in context |
| title_full | Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in context |
| title_fullStr | Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in context |
| title_full_unstemmed | Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in context |
| title_short | Guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients: 2023 updateResearch in context |
| title_sort | guideline for the management of fatigue in children and adolescents with cancer or pediatric hematopoietic cell transplant recipients 2023 updateresearch in context |
| topic | Practice guideline Fatigue Pediatric oncology |
| url | http://www.sciencedirect.com/science/article/pii/S2589537023003243 |
| work_keys_str_mv | AT priyapatel guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT pauladrobinson guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT patrickvandertorre guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT deborahtomlinson guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT jenniferseelisch guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT sapnaoberoi guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT jessicaemorgan guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT pamelashinds guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT miriamgotte guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT faithgibson guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT nathanduong guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT haileydavis guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT snicoleculosreed guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT daniellecataudella guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT vanessamiranda guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT lleedupuis guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext AT lilliansung guidelineforthemanagementoffatigueinchildrenandadolescentswithcancerorpediatrichematopoieticcelltransplantrecipients2023updateresearchincontext |