Ménétrier’s Disease: Its Mimickers and Pathogenesis
Ménétrier’s disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Ménétrier’s disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand...
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Format: | Article |
Language: | English |
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Korean Society of Pathologists & the Korean Society for Cytopathology
2016-01-01
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Series: | Journal of Pathology and Translational Medicine |
Subjects: | |
Online Access: | http://www.jpatholtm.org/upload/pdf/jptm-2015-09-15.pdf |
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author | Won Jae Huh Robert J. Coffey Mary Kay Washington |
author_facet | Won Jae Huh Robert J. Coffey Mary Kay Washington |
author_sort | Won Jae Huh |
collection | DOAJ |
description | Ménétrier’s disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Ménétrier’s disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand, transforming growth factor alpha, contributes to the pathogenesis of this disorder. In this review, we will discuss disease entities that can mimic Ménétrier’s disease and the role of EGFR signaling in Ménétrier’s disease. |
first_indexed | 2024-12-10T15:54:43Z |
format | Article |
id | doaj.art-a957b9f85eea4293bf3283172b3f0d07 |
institution | Directory Open Access Journal |
issn | 2383-7837 2383-7845 |
language | English |
last_indexed | 2024-12-10T15:54:43Z |
publishDate | 2016-01-01 |
publisher | Korean Society of Pathologists & the Korean Society for Cytopathology |
record_format | Article |
series | Journal of Pathology and Translational Medicine |
spelling | doaj.art-a957b9f85eea4293bf3283172b3f0d072022-12-22T01:42:42ZengKorean Society of Pathologists & the Korean Society for CytopathologyJournal of Pathology and Translational Medicine2383-78372383-78452016-01-01501101610.4132/jptm.2015.09.1516580Ménétrier’s Disease: Its Mimickers and PathogenesisWon Jae Huh0Robert J. Coffey1Mary Kay Washington2 Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USAMénétrier’s disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Ménétrier’s disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand, transforming growth factor alpha, contributes to the pathogenesis of this disorder. In this review, we will discuss disease entities that can mimic Ménétrier’s disease and the role of EGFR signaling in Ménétrier’s disease.http://www.jpatholtm.org/upload/pdf/jptm-2015-09-15.pdfMénétrier’s diseaseGastric polypTransforming growth factor alpha |
spellingShingle | Won Jae Huh Robert J. Coffey Mary Kay Washington Ménétrier’s Disease: Its Mimickers and Pathogenesis Journal of Pathology and Translational Medicine Ménétrier’s disease Gastric polyp Transforming growth factor alpha |
title | Ménétrier’s Disease: Its Mimickers and Pathogenesis |
title_full | Ménétrier’s Disease: Its Mimickers and Pathogenesis |
title_fullStr | Ménétrier’s Disease: Its Mimickers and Pathogenesis |
title_full_unstemmed | Ménétrier’s Disease: Its Mimickers and Pathogenesis |
title_short | Ménétrier’s Disease: Its Mimickers and Pathogenesis |
title_sort | menetrier s disease its mimickers and pathogenesis |
topic | Ménétrier’s disease Gastric polyp Transforming growth factor alpha |
url | http://www.jpatholtm.org/upload/pdf/jptm-2015-09-15.pdf |
work_keys_str_mv | AT wonjaehuh menetriersdiseaseitsmimickersandpathogenesis AT robertjcoffey menetriersdiseaseitsmimickersandpathogenesis AT marykaywashington menetriersdiseaseitsmimickersandpathogenesis |