RETRACTED ARTICLE: Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis
Abstract Indoleamine 2,3 dioxygenase-1 (IDO1) catalyzes tryptophan-kynurenine metabolism in many inflammatory and cancer diseases. Of note, acute inflammation that occurs immediately after heart injury is essential for neonatal cardiomyocyte proliferation and heart regeneration. However, the IDO1-ca...
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | Article |
| Langue: | English |
| Publié: |
Nature Portfolio
2022-10-01
|
| Collection: | Nature Communications |
| Accès en ligne: | https://doi.org/10.1038/s41467-022-33734-7 |