Clinical features of infectious spondylitis in patients with COVID-19
Tumors and inflammatory diseases of the spine85 Khirurgiya Pozvonochnika (Journal of spine surgery) 2023;20(1):85–92I.V. Yesin et al., 2023 Objective. To analyze the clinical features of the course of infectious spondylitis in patients with COVID-19. Material and Methods. A continuous retrospecti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ministry of Health of Russian Federation, Federal State Budgetary Institution "Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan"
2023-03-01
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| Series: | Хирургия позвоночника |
| Subjects: | |
| Online Access: | https://www.spinesurgery.ru/jour/article/view/1993/1983 |
| Summary: | Tumors and inflammatory diseases of the spine85
Khirurgiya Pozvonochnika (Journal of spine surgery) 2023;20(1):85–92I.V. Yesin et al., 2023
Objective. To analyze the clinical features of the course of infectious spondylitis in patients with COVID-19.
Material and Methods. A continuous retrospective study was performed with the analysis of medical records of 52 patients with infectious
spondylitis who were treated in 2021–2022. The patients were divided into two groups: the study group (n = 24) – with a history of a
new coronavirus infection; and the control group (n = 28) – without coronavirus infection.
Results. The features of infectious spondylitis in patients with COVID-19 are the predominance of facultative anaerobic gram-negative
flora in the focus of infection, a higher frequency of multilevel lesions, a tendency to increase the number of negative results of surgical
treatment, and a chronic protracted course. At the same time, the course of infectious spondylitis associated with COVID-19 is accompa-
nied by less destructive changes in the affected segment leading to a violation of the supporting function of the spine. Nevertheless, there
is a statistically significant increase in the period of relief of the inflammatory process in the spine in these patients: 18.04 ± 3.84 weeks in
the study group and 10.08 ± 2.34 weeks in the control group (Uemp < 240; p = 0.001).
Conclusion. The secondary infectious lesion of the spine against the background of a new coronavirus infection is caused by gram-negative
pathogens in the vast majority of cases, proceeds without severe bone destruction, with a tendency to a chronic protracted course. Surgi-
cal treatment of COVID-associated spondylitis is associated with a higher risk of postoperative complications. |
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| ISSN: | 1810-8997 2313-1497 |