Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopy
Abstract Purpose To assess the efficacy of double-balloon endoscopy (DBE) for the detection of small-bowel strictures in Crohn’s disease (CD). Methods This tertiary-referral hospital cohort study was conducted between January 2018 and May 2022. CD patients with symptoms of small-bowel stricture were...
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | BMC Gastroenterology |
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| Online Access: | https://doi.org/10.1186/s12876-023-02839-8 |
| _version_ | 1797774171848048640 |
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| author | Jing Hu Juan Wu Peipei Zhang Naizhong Hu Qiao Mei Xingwang Wu Wei Han |
| author_facet | Jing Hu Juan Wu Peipei Zhang Naizhong Hu Qiao Mei Xingwang Wu Wei Han |
| author_sort | Jing Hu |
| collection | DOAJ |
| description | Abstract Purpose To assess the efficacy of double-balloon endoscopy (DBE) for the detection of small-bowel strictures in Crohn’s disease (CD). Methods This tertiary-referral hospital cohort study was conducted between January 2018 and May 2022. CD patients with symptoms of small-bowel stricture were enrolled sequentially. All of the patients were subjected to both computed tomography enterography (CTE) and DBE, and their symptoms of stricture were assessed using the Crohn’s Disease Obstructive Score (CDOS). The diagnostic yield of DBE was compared to that of CTE, and the relationship between the DBE findings and CDOS was investigated. The factors influencing the DBE diagnosis were examined using Cox regression analysis. Results This study included 165 CD patients. The CDOS scores were higher in 95 patients and lower in 70 patients. DBE detected 92.7% (153/165) and CTE detected 85.5% (141/165) of the strictures. The DBE diagnostic yields were 94.7% (90/95) in the high CDOS patients and 91.4% (64/70) in the low CDOS patients (P = 0.13). Patients with a history of abdominal surgery and abscess had a lower diagnosis rate in the multivariate analysis. Conclusion DBE has been demonstrated to be an efficient diagnostic method for detecting small bowel strictures in CD patients. Additionally, there was no difference in the diagnostic yields between patients with low and high obstructive scores. |
| first_indexed | 2024-03-12T22:17:06Z |
| format | Article |
| id | doaj.art-a96e0fe9a1b143b59fd03c2d41c59bd4 |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-03-12T22:17:06Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-a96e0fe9a1b143b59fd03c2d41c59bd42023-07-23T11:16:06ZengBMCBMC Gastroenterology1471-230X2023-07-012311810.1186/s12876-023-02839-8Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopyJing Hu0Juan Wu1Peipei Zhang2Naizhong Hu3Qiao Mei4Xingwang Wu5Wei Han6Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gastroenterology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gastroenterology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gastroenterology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gastroenterology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Radiology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gastroenterology, The First Affiliated Hospital of Anhui Medical UniversityAbstract Purpose To assess the efficacy of double-balloon endoscopy (DBE) for the detection of small-bowel strictures in Crohn’s disease (CD). Methods This tertiary-referral hospital cohort study was conducted between January 2018 and May 2022. CD patients with symptoms of small-bowel stricture were enrolled sequentially. All of the patients were subjected to both computed tomography enterography (CTE) and DBE, and their symptoms of stricture were assessed using the Crohn’s Disease Obstructive Score (CDOS). The diagnostic yield of DBE was compared to that of CTE, and the relationship between the DBE findings and CDOS was investigated. The factors influencing the DBE diagnosis were examined using Cox regression analysis. Results This study included 165 CD patients. The CDOS scores were higher in 95 patients and lower in 70 patients. DBE detected 92.7% (153/165) and CTE detected 85.5% (141/165) of the strictures. The DBE diagnostic yields were 94.7% (90/95) in the high CDOS patients and 91.4% (64/70) in the low CDOS patients (P = 0.13). Patients with a history of abdominal surgery and abscess had a lower diagnosis rate in the multivariate analysis. Conclusion DBE has been demonstrated to be an efficient diagnostic method for detecting small bowel strictures in CD patients. Additionally, there was no difference in the diagnostic yields between patients with low and high obstructive scores.https://doi.org/10.1186/s12876-023-02839-8Double-balloon endoscopyCT enterographyCrohn’s diseaseSmall bowel stricture |
| spellingShingle | Jing Hu Juan Wu Peipei Zhang Naizhong Hu Qiao Mei Xingwang Wu Wei Han Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopy BMC Gastroenterology Double-balloon endoscopy CT enterography Crohn’s disease Small bowel stricture |
| title | Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopy |
| title_full | Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopy |
| title_fullStr | Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopy |
| title_full_unstemmed | Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopy |
| title_short | Evaluation of symptomatic small bowel stricture in Crohn’s disease by double-balloon endoscopy |
| title_sort | evaluation of symptomatic small bowel stricture in crohn s disease by double balloon endoscopy |
| topic | Double-balloon endoscopy CT enterography Crohn’s disease Small bowel stricture |
| url | https://doi.org/10.1186/s12876-023-02839-8 |
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