Approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international study
Introduction. Atrial fibrillation (AF), the most common arrhythmia that requires treatment, does not come out of the focus of researchers. Monitoring its prevalence and effects of therapy is a good guideline approach to the growing population of patients in which this arrhythmia occurs. Obj...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2015-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2015/0370-81791510551P.pdf |
| _version_ | 1818325315784540160 |
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| author | Pavlović Siniša U. Kirćanski Bratislav Radovanović Nikola Raspopović Srđan Jovanović Velibor Nikčević Gabrijela Živković Mirjana Milašinović Goran |
| author_facet | Pavlović Siniša U. Kirćanski Bratislav Radovanović Nikola Raspopović Srđan Jovanović Velibor Nikčević Gabrijela Živković Mirjana Milašinović Goran |
| author_sort | Pavlović Siniša U. |
| collection | DOAJ |
| description | Introduction. Atrial fibrillation (AF), the most common arrhythmia that
requires treatment, does not come out of the focus of researchers. Monitoring
its prevalence and effects of therapy is a good guideline approach to the
growing population of patients in which this arrhythmia occurs. Objective.
The aim of the study was to evaluate the efficacy of treatment of AF and
cardiovascular profiles in the observed population. Methods. In this
observational, cross-sectional, multicenter, international study, 584
patients in 30 centers in Serbia and Slovenia, older than 18 years and with
AF or in sinus rhythm with a history of AF, were included. The assessment of
the efficacy of treatment of AF was performed by analyzing the frequency of
adequate therapeutic effect of medication in rhythm or frequency control in
patients with AF. Results. The results confirmed that the highest incidence
of AF duration is more than seven days, and is accompanied by symptoms.
Inadequate frequency regulation was registered at 8.9% of patients.
Hypertension was registered in two-thirds of all patients, while other
cardiovascular risk factors were registered in about one-third of patients.
An echocardiographic finding in the group of patients with AF confirms
generally adequate left ventricular function with a slightly enlarged left
atrium (4.6±0.8 cm). Increasing age and time from the first episode of AF
decreases the probability of maintaining sinus rhythm, while symptomatic AF
had a positive impact on the presence of sinus rhythm. Propafenone, sotalol
and amiodarone showed a statistically significant connection with a positive
therapeutic response, while β-blockers had a negative impact on the
probability of establishing and maintaining sinus rhythm. Conclusion.
Characteristics of therapeutic approaches, risks, comorbidity of patient
populations in Slovenia and Serbia correspond to the fullest extent with the
recommendations for good clinical practice, which further stresses the need
for extensive measures in these regions. |
| first_indexed | 2024-12-13T11:42:32Z |
| format | Article |
| id | doaj.art-a96e9daac6c647b4b298a730eb1b1928 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-12-13T11:42:32Z |
| publishDate | 2015-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-a96e9daac6c647b4b298a730eb1b19282022-12-21T23:47:36ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952015-01-011439-1055155810.2298/SARH1510551P0370-81791510551PApproach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international studyPavlović Siniša U.0Kirćanski Bratislav1Radovanović Nikola2Raspopović Srđan3Jovanović Velibor4Nikčević Gabrijela5Živković Mirjana6Milašinović Goran7Clinical Center of Serbia, Pacemaker center, Belgrade + School of Medicine, BelgradeClinical Center of Serbia, Pacemaker center, BelgradeClinical Center of Serbia, Pacemaker center, BelgradeClinical Center of Serbia, Pacemaker center, BelgradeClinical Center of Serbia, Pacemaker center, BelgradeClinical Center of Serbia, Pacemaker center, BelgradeClinical Center of Serbia, Pacemaker center, BelgradeClinical Center of Serbia, Pacemaker center, Belgrade + School of Medicine, BelgradeIntroduction. Atrial fibrillation (AF), the most common arrhythmia that requires treatment, does not come out of the focus of researchers. Monitoring its prevalence and effects of therapy is a good guideline approach to the growing population of patients in which this arrhythmia occurs. Objective. The aim of the study was to evaluate the efficacy of treatment of AF and cardiovascular profiles in the observed population. Methods. In this observational, cross-sectional, multicenter, international study, 584 patients in 30 centers in Serbia and Slovenia, older than 18 years and with AF or in sinus rhythm with a history of AF, were included. The assessment of the efficacy of treatment of AF was performed by analyzing the frequency of adequate therapeutic effect of medication in rhythm or frequency control in patients with AF. Results. The results confirmed that the highest incidence of AF duration is more than seven days, and is accompanied by symptoms. Inadequate frequency regulation was registered at 8.9% of patients. Hypertension was registered in two-thirds of all patients, while other cardiovascular risk factors were registered in about one-third of patients. An echocardiographic finding in the group of patients with AF confirms generally adequate left ventricular function with a slightly enlarged left atrium (4.6±0.8 cm). Increasing age and time from the first episode of AF decreases the probability of maintaining sinus rhythm, while symptomatic AF had a positive impact on the presence of sinus rhythm. Propafenone, sotalol and amiodarone showed a statistically significant connection with a positive therapeutic response, while β-blockers had a negative impact on the probability of establishing and maintaining sinus rhythm. Conclusion. Characteristics of therapeutic approaches, risks, comorbidity of patient populations in Slovenia and Serbia correspond to the fullest extent with the recommendations for good clinical practice, which further stresses the need for extensive measures in these regions.http://www.doiserbia.nb.rs/img/doi/0370-8179/2015/0370-81791510551P.pdfatrial fibrillationcardiovascular risk factorstreatment |
| spellingShingle | Pavlović Siniša U. Kirćanski Bratislav Radovanović Nikola Raspopović Srđan Jovanović Velibor Nikčević Gabrijela Živković Mirjana Milašinović Goran Approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international study Srpski Arhiv za Celokupno Lekarstvo atrial fibrillation cardiovascular risk factors treatment |
| title | Approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international study |
| title_full | Approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international study |
| title_fullStr | Approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international study |
| title_full_unstemmed | Approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international study |
| title_short | Approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile: Multicentric international study |
| title_sort | approach to the treatment of atrial fibrillation in patients with cardiovascular risk profile multicentric international study |
| topic | atrial fibrillation cardiovascular risk factors treatment |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2015/0370-81791510551P.pdf |
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