Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations
The current study was carried out to evaluate multicomponent pattern, biological and enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the fact that these plants are commonly used as traditional food supplements in Turkish regions. The extracts were character...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2017-01-01
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| Series: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/14756366.2016.1235041 |
| _version_ | 1811341936555982848 |
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| author | Marcello Locatelli Gokhan Zengin Ahmet Uysal Simone Carradori Elisa De Luca Giuseppe Bellagamba Abdurrahman Aktumsek Irina Lazarova |
| author_facet | Marcello Locatelli Gokhan Zengin Ahmet Uysal Simone Carradori Elisa De Luca Giuseppe Bellagamba Abdurrahman Aktumsek Irina Lazarova |
| author_sort | Marcello Locatelli |
| collection | DOAJ |
| description | The current study was carried out to evaluate multicomponent pattern, biological and enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the fact that these plants are commonly used as traditional food supplements in Turkish regions. The extracts were characterized for free anthraquinones and phenolics to obtain a specific chemical fingerprint useful for quality control. These analyzes were coupled to biological and enzymatic activities in order to obtain comprehensive information of the natural product. Free anthraquinones and phenolics were determined using validated HPLC-PDA methods. Antioxidant properties were determined by different procedures including free radical scavenging, reducing power, phosphomolybdenum and metal chelating assays. Ames assay was performed to evaluate mutagenic/antimutagenic properties. Enzyme inhibitory activities were tested against cholinesterase, tyrosinase, α-amylase and α-glucosidase. From the herein reported results, Asphodeline could be valuable for the production of bioactive products or food supplements for cosmetic and pharmaceutical industries. |
| first_indexed | 2024-04-13T19:02:44Z |
| format | Article |
| id | doaj.art-a96f5a2626bd4111a6d40bfd5bf953a9 |
| institution | Directory Open Access Journal |
| issn | 1475-6366 1475-6374 |
| language | English |
| last_indexed | 2024-04-13T19:02:44Z |
| publishDate | 2017-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Enzyme Inhibition and Medicinal Chemistry |
| spelling | doaj.art-a96f5a2626bd4111a6d40bfd5bf953a92022-12-22T02:34:03ZengTaylor & Francis GroupJournal of Enzyme Inhibition and Medicinal Chemistry1475-63661475-63742017-01-01321606710.1080/14756366.2016.12350411235041Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulationsMarcello Locatelli0Gokhan Zengin1Ahmet Uysal2Simone Carradori3Elisa De Luca4Giuseppe Bellagamba5Abdurrahman Aktumsek6Irina Lazarova7University “G. d’Annunzio” of Chieti-PescaraSelcuk UniversitySelcuk UniversityUniversity “G. d’Annunzio” of Chieti-PescaraUniversity “G. d’Annunzio” of Chieti-PescaraUniversity “G. d’Annunzio” of Chieti-PescaraSelcuk UniversityMedical University of SofiaThe current study was carried out to evaluate multicomponent pattern, biological and enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the fact that these plants are commonly used as traditional food supplements in Turkish regions. The extracts were characterized for free anthraquinones and phenolics to obtain a specific chemical fingerprint useful for quality control. These analyzes were coupled to biological and enzymatic activities in order to obtain comprehensive information of the natural product. Free anthraquinones and phenolics were determined using validated HPLC-PDA methods. Antioxidant properties were determined by different procedures including free radical scavenging, reducing power, phosphomolybdenum and metal chelating assays. Ames assay was performed to evaluate mutagenic/antimutagenic properties. Enzyme inhibitory activities were tested against cholinesterase, tyrosinase, α-amylase and α-glucosidase. From the herein reported results, Asphodeline could be valuable for the production of bioactive products or food supplements for cosmetic and pharmaceutical industries.http://dx.doi.org/10.1080/14756366.2016.1235041Asphodelineanthraquinonesbiological activity and bioactive compoundsmulticomponent patternphenolics |
| spellingShingle | Marcello Locatelli Gokhan Zengin Ahmet Uysal Simone Carradori Elisa De Luca Giuseppe Bellagamba Abdurrahman Aktumsek Irina Lazarova Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations Journal of Enzyme Inhibition and Medicinal Chemistry Asphodeline anthraquinones biological activity and bioactive compounds multicomponent pattern phenolics |
| title | Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations |
| title_full | Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations |
| title_fullStr | Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations |
| title_full_unstemmed | Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations |
| title_short | Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations |
| title_sort | multicomponent pattern and biological activities of seven asphodeline taxa potential sources of natural functional ingredients for bioactive formulations |
| topic | Asphodeline anthraquinones biological activity and bioactive compounds multicomponent pattern phenolics |
| url | http://dx.doi.org/10.1080/14756366.2016.1235041 |
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