IGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis

IGF2BP2-induced circRUNX1 facilitates the growth and metastasis of esophageal squamous cell carcinoma through miR-449b-5p/FOXP3 axis

Abstract Background Esophageal squamous cell carcinoma (ESCC) is one of the most common digestive malignancies with relatively high morbidity and mortality. Emerging evidence suggests circular RNAs (circRNAs) play critical roles in tumor cell malignancy. However, the biological function and clinical...

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Bibliographic Details
Main Authors: Chang Wang, Mingxia Zhou, Peiyu Zhu, Chenxi Ju, Jinxiu Sheng, Dan Du, Junhu Wan, Huiqing Yin, Yurong Xing, Hongle Li, Jing He, Fucheng He
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Esophageal squamous cell carcinoma (ESCC)
CircRUNX1
FOXP3
IGF2BP2
Biomarker
Online Access:https://doi.org/10.1186/s13046-022-02550-8

Internet

https://doi.org/10.1186/s13046-022-02550-8

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